Skip to main content

Articles

Page 9 of 12

  1. Sexual behavior of HIV-positive youths, whether infected perinatally, through risky behavior or other ways, is not substantially different from that of HIV-uninfected peers. Because of highly active antiretrov...

    Authors: Nadia T Kancheva Landolt, Sudrak Lakhonphon and Jintanat Ananworanich

    Citation: AIDS Research and Therapy 2011 8:19

    Content type: Review

    Published on:

  2. To evaluate the efficacy of highly-active antiretroviral therapy (HAART) in individuals taking cytochrome P450 enzyme-inducing antiepileptics (EI-EADs), we evaluated the virologic response to HAART with or wit...

    Authors: Jason F Okulicz, Greg A Grandits, Jacqueline A French, Jomy M George, David M Simpson, Gretchen L Birbeck, Anuradha Ganesan, Amy C Weintrob, Nancy Crum-Cianflone, Tahaniyat Lalani and Michael L Landrum

    Citation: AIDS Research and Therapy 2011 8:18

    Content type: Research

    Published on:

  3. Minocycline is a tetracycline antibiotic that has been shown to attenuate central nervous system (CNS) lentivirus infection, immune activation, and brain injury in model systems. To initiate assessment of mino...

    Authors: Emily L Ho, Serena S Spudich, Evelyn Lee, Dietmar Fuchs, Elizabeth Sinclair and Richard W Price

    Citation: AIDS Research and Therapy 2011 8:17

    Content type: Research

    Published on:

  4. The potential risk of HIV-1 infection following human bite although epidemiologically insignificant, but it is biologically possible. There are anecdotal reports of HIV transmission by human bites particularly...

    Authors: Alaka K Deshpande, Shivaji K Jadhav and Atmaram H Bandivdekar

    Citation: AIDS Research and Therapy 2011 8:16

    Content type: Case report

    Published on:

  5. Our goal was to illustrate a method for making indirect treatment comparisons in the absence of head-to-head trials, by portraying the derivation of published efficacies for prophylaxis regimens of HIV-related...

    Authors: Jennifer Chu, Caroline E Sloan, Kenneth A Freedberg, Yazdan Yazdanpanah and Elena Losina

    Citation: AIDS Research and Therapy 2011 8:14

    Content type: Short report

    Published on:

  6. HIV/AIDS has orphaned 11.6 million children in sub-Saharan Africa. Expanded antiretroviral therapy (ART) use may reduce AIDS orphanhood by decreasing adult mortality and population-level HIV transmission.

    Authors: Aranka Anema, Christopher G Au-Yeung, Michel Joffres, Angela Kaida, Krisztina Vasarhelyi, Steve Kanters, Julio SG Montaner and Robert S Hogg

    Citation: AIDS Research and Therapy 2011 8:13

    Content type: Research

    Published on:

  7. The objective of this study is to identify the critical formulation parameters controlling distribution and function for the rectal administration of microbicides in humans. Four placebo formulations were desi...

    Authors: Lin Wang, Roger L Schnaare, Charlene Dezzutti, Peter A Anton and Lisa C Rohan

    Citation: AIDS Research and Therapy 2011 8:12

    Content type: Research

    Published on:

  8. Sub-Saharan Africa remains the region most heavily affected by HIV. In 2008, the region accounted for 67% of HIV infections worldwide, the region also accounted for 72% of the world's AIDS-related deaths in 20...

    Authors: Rhoune Ochako, Dunstone Ulwodi, Purity Njagi, Steven Kimetu and Aggrey Onyango

    Citation: AIDS Research and Therapy 2011 8:11

    Content type: Research

    Published on:

  9. HIV remains responsible for an estimated 40% of mortality in South African pregnant women and their children. To address these avoidable deaths, eligibility criteria for antiretroviral therapy (ART) in pregnan...

    Authors: Courtenay Sprague, Matthew F Chersich and Vivian Black

    Citation: AIDS Research and Therapy 2011 8:10

    Content type: Research

    Published on:

  10. In HIV-1 infected patients, increase of liver enzymes may be mainly due to viral coinfections, alcohol intake, hepatotoxic drugs or autoimmune diseases. Three cases of aminotransferase elevation occurred durin...

    Authors: Antonella Esposito, Valentina Conti, Maria Cagliuso, Daniele Pastori, Alessandra Fantauzzi and Ivano Mezzaroma

    Citation: AIDS Research and Therapy 2011 8:9

    Content type: Case report

    Published on:

  11. Access to free antiretroviral therapy in Sub-Saharan Africa has been steadily increasing. The success of large-scale antiretroviral therapy programs depends on early initiation of HIV/AIDs care. The purpose of...

    Authors: Yeshewas Abaynew, Amare Deribew and Kebede Deribe

    Citation: AIDS Research and Therapy 2011 8:8

    Content type: Research

    Published on:

  12. Although being considered as a rarely observed HIV-1 protease mutation in clinical isolates, the L76V-prevalence increased 1998-2008 in some European countries most likely due to the approval of Lopinavir, Amp...

    Authors: Frank Wiesmann, Jan Vachta, Robert Ehret, Hauke Walter, Rolf Kaiser, Martin Stürmer, André Tappe, Martin Däumer, Thomas Berg, Gudrun Naeth, Patrick Braun and Heribert Knechten

    Citation: AIDS Research and Therapy 2011 8:7

    Content type: Short report

    Published on:

  13. We describe two patients who did not experience a viral rebound after cessation of HAART which was initiated for progressive disease. CD4 T-cell count remained stable in one patient and progressively declined ...

    Authors: Ellen Van Gulck, Leo Heyndrickx, Lotte Bracke, Sandra Coppens, Eric Florence, Anne Buvé, Paul Lewi and Guido Vanham

    Citation: AIDS Research and Therapy 2011 8:6

    Content type: Case report

    Published on:

  14. The purpose of this study was to examine the relationship between the Medical Outcomes Study-HIV Health Survey (MOS-HIV) and the SF-12v2 to determine if the latter is adequate to assess the health-related qual...

    Authors: Allyson Ion, Wenjie Cai, Dawn Elston, Eleanor Pullenayegum, Fiona Smaill and Marek Smieja

    Citation: AIDS Research and Therapy 2011 8:5

    Content type: Research

    Published on:

  15. South Africa has a huge burden of illness due to HIV infection. Many health care workers managing HIV infected patients, particularly those in rural areas and primary care health facilities, have minimal acces...

    Authors: Briony S Chisholm, Karen Cohen, Marc Blockman, Hans-Friedemann Kinkel, Tamara J Kredo and Annoesjka M Swart

    Citation: AIDS Research and Therapy 2011 8:4

    Content type: Research

    Published on:

  16. In many preclinical AIDS research studies, antiretroviral therapy (ART) is administered to experimentally simian immunodeficiency (SIV)-infected rhesus macaques for reduction of viral load to undetectable leve...

    Authors: Brigitte E Sanders-Beer, Yvette Y Spano, Dawn Golighty, Abigail Lara, Diane Hebblewaite, Lourdes Nieves-Duran, Lowrey Rhodes and Keith G Mansfield

    Citation: AIDS Research and Therapy 2011 8:3

    Content type: Research

    Published on:

  17. Among HIV-infected persons initiating highly active antiretroviral therapy (HAART), early CD4+ lymphocyte count increases are well described. However, whether CD4+ levels continue to increase or plateau after ...

    Authors: Alan R Lifson, Elizabeth M Krantz, Lynn E Eberly, Matthew J Dolan, Vincent C Marconi, Amy C Weintrob, Nancy F Crum-Cianflone, Anuradha Ganesan, Patricia L Grambsch and Brian K Agan

    Citation: AIDS Research and Therapy 2011 8:2

    Content type: Research

    Published on:

  18. Combinatorial RNA interference (co-RNAi) approaches are needed to account for viral variability in treating HIV-1 with RNAi, as single short hairpin RNAs (shRNA) are rapidly rendered ineffective by resistant s...

    Authors: Glen J Mcintyre, Jennifer L Groneman, Yi-Hsin Yu, Anna Tran and Tanya L Applegate

    Citation: AIDS Research and Therapy 2011 8:1

    Content type: Research

    Published on:

  19. Appendicitis is a frequent surgical emergency worldwide. The present study was conducted to determine the prevalence of HIV, and the association of infection with clinical, intraoperative and histological find...

    Authors: Geofrey C Giiti, Humphrey D Mazigo, Jorg Heukelbach and William Mahalu

    Citation: AIDS Research and Therapy 2010 7:47

    Content type: Research

    Published on:

  20. Highly active antiretroviral therapy (HAART) improves the immune function and decreases morbidity, mortality and opportunistic infections (OIs) in HIV-infected patients. However, since the use of HAART, immune...

    Authors: Kahsay Huruy, Afework Kassu, Andargachew Mulu and Yemataw Wondie

    Citation: AIDS Research and Therapy 2010 7:46

    Content type: Research

    Published on:

  21. We assessed CD4 count at initial presentation for HIV care among ≥50-year-olds from 1997-2007 in 13 US and Canadian clinical cohorts and compared to <50-year-olds. 44,491 HIV-infected individuals in the North ...

    Authors: Keri N Althoff, Kelly A Gebo, Stephen J Gange, Marina B Klein, John T Brooks, Robert S Hogg, Ronald J Bosch, Michael A Horberg, Michael S Saag, Mari M Kitahata, Joseph J Eron, Sonia Napravnik, Sean B Rourke, M John Gill, Benigno Rodriguez, Timothy R Sterling…

    Citation: AIDS Research and Therapy 2010 7:45

    Content type: Short report

    Published on:

  22. In the HAART era, the incidence of HIV-associated non-Hodgkin lymphoma (NHL) is decreasing. We describe cases of NHL among patients with multi-class antiretroviral resistance diagnosed rapidly after initiating...

    Authors: Gregory D Huhn, Sheila Badri, Sonia Vibhakar, Frank Tverdek, Christopher Crank, Ronald Lubelchek, Blake Max, David Simon, Beverly Sha, Oluwatoyin Adeyemi, Patricia Herrera, Allan Tenorio, Harold Kessler and David Barker

    Citation: AIDS Research and Therapy 2010 7:44

    Content type: Short report

    Published on:

  23. The population of HIV replicating within a host consists of independently evolving and interacting sub-populations that can be genetically distinct within anatomical compartments. HIV replicating within the br...

    Authors: Alexander G Holman, Megan E Mefford, Niall O'Connor and Dana Gabuzda

    Citation: AIDS Research and Therapy 2010 7:43

    Content type: Research

    Published on:

  24. Although antiretroviral therapy (ART) has proven its success against HIV-1, the long lifespan of infected cells and viral latency prevent eradication. In this study we analyzed the sensitivity to ART of HIV-1 ...

    Authors: Edwin J Heeregrave, Mark J Geels, Elly Baan, Renee M van der Sluis, William A Paxton and Georgios Pollakis

    Citation: AIDS Research and Therapy 2010 7:42

    Content type: Research

    Published on:

  25. Vitamin D is an important determinant of bone health and also plays a major role in the regulation of the immune system. Interestingly, vitamin D status before the start of highly active antiretroviral therapy...

    Authors: Anali Conesa-Botella, Eric Florence, Lutgarde Lynen, Robert Colebunders, Joris Menten and Rodrigo Moreno-Reyes

    Citation: AIDS Research and Therapy 2010 7:40

    Content type: Research

    Published on:

  26. Good adherence to antiretroviral therapy is necessary to achieve the best virological response, lower the risk that drug resistance will develop, and reduce morbidity and mortality. Little is known about the r...

    Authors: Ayele Tiyou, Tefera Belachew, Fisehaye Alemseged and Sibhatu Biadgilign

    Citation: AIDS Research and Therapy 2010 7:39

    Content type: Research

    Published on:

  27. As second-line antiretroviral treatment (ART) becomes more accessible in resource-limited settings (RLS), the need for more affordable monitoring tools such as point-of-care viral load assays and simplified ge...

    Authors: Kim Steegen, Michelle Bronze, Elke Van Craenenbroeck, Bart Winters, Koen Van der Borght, Carole L Wallis, Wendy Stevens, Tobias F Rinke de Wit and Lieven J Stuyver

    Citation: AIDS Research and Therapy 2010 7:38

    Content type: Research

    Published on:

  28. During stavudine phase-out plan in developing countries, tenofovir is used to substitute stavudine. However, knowledge regarding whether there is any difference of the frequency of renal injury between tenofov...

    Authors: Weerawat Manosuthi, Wiroj Mankatitham, Aroon Lueangniyomkul, Wisit Prasithsirikul, Preecha Tantanathip, Busakorn Suntisuklappon, Anongnuch Narkksoksung, Samruay Nilkamhang and Somnuek Sungkanuparph

    Citation: AIDS Research and Therapy 2010 7:37

    Content type: Research

    Published on:

  29. Immune reconstitution inflammatory syndrome (IRIS) is an important complication of HAART in sub-Saharan Africa, where opportunistic infections (OIs) including mycobacteria and cryptococcus are common. The immu...

    Authors: Catherine M Worsley, Melinda S Suchard, Wendy S Stevens, Annelies Van Rie and David M Murdoch

    Citation: AIDS Research and Therapy 2010 7:36

    Content type: Research

    Published on:

  30. We present an innovative approach to healthcare worker (HCW) training using mobile phones as a personal learning environment.

    Authors: Maria Zolfo, David Iglesias, Carlos Kiyan, Juan Echevarria, Luis Fucay, Ellar Llacsahuanga, Inge de Waard, Victor Suàrez, Walter Castillo Llaque and Lutgarde Lynen

    Citation: AIDS Research and Therapy 2010 7:35

    Content type: Research

    Published on:

  31. Lipoprotein profiles in HIV-infected African women have not been well described. We assessed associations of lipoprotein levels and cardiovascular risk with HIV-infection and CD4 count in Rwandan women.

    Authors: Kathryn Anastos, François Ndamage, Dalian Lu, Mardge H Cohen, Qiuhu Shi, Jason Lazar, Venerand Bigirimana and Eugene Mutimura

    Citation: AIDS Research and Therapy 2010 7:34

    Content type: Research

    Published on:

  32. Few data are available to guide programmatic solutions to the overlapping problems of undernutrition and HIV infection. We evaluated the impact of food assistance on patient outcomes in a comprehensive HIV pro...

    Authors: Louise C Ivers, Yuchiao Chang, J Gregory Jerome and Kenneth A Freedberg

    Citation: AIDS Research and Therapy 2010 7:33

    Content type: Research

    Published on:

  33. The 516G > T polymorphism in exon 4 of the CYP2B6 gene has been associated with increased plasma Efavirenz (EFV) concentrations. EFV concentrations greater than the recommended therapeutic range have been associa...

    Authors: Verena Gounden, Chantal van Niekerk, Tracy Snyman and Jaya A George

    Citation: AIDS Research and Therapy 2010 7:32

    Content type: Research

    Published on:

  34. A correlation between increase in the integration of Human Immunodeficiency virus-1 (HIV-1) cDNA and cell death was previously established. Here we show that combination of peptides that stimulate integration ...

    Authors: Aviad Levin, Zvi Hayouka, Assaf Friedler and Abraham Loyter

    Citation: AIDS Research and Therapy 2010 7:31

    Content type: Short report

    Published on:

  35. Effective antiretroviral therapy reduces HIV-1 RNA levels, improves CD4 T-cell counts, and lowers the risk of opportunistic infections and malignancies. Interleukin-2 (IL-2) has been shown to increase CD4 T-ce...

    Authors: Ronald J Bosch, Richard B Pollard, Alan Landay, Evgenia Aga, Lawrence Fox and Ronald Mitsuyasu

    Citation: AIDS Research and Therapy 2010 7:30

    Content type: Research

    Published on:

  36. This study aimed to evaluate the prevalence and predictors of AIDS-related complicated cryptococcal meningitis. The outcome was complicated cryptococcal meningitis: prolonged (≥ 14 days) altered mental status,...

    Authors: Edward R Cachay, Joseph Caperna, Amy M Sitapati, Hamta Jafari, Sean Kandel and William C Mathews

    Citation: AIDS Research and Therapy 2010 7:29

    Content type: Research

    Published on:

  37. HIV-1 Rev protein regulates the expression of HIV-1 transcripts by binding to a highly structured stem loop structure called the Rev Responsive Element (RRE) present in the genomic and partially spliced RNAs. ...

    Authors: Yogeshwar Sharma, Ujjwal Neogi, Vikas Sood, Snigdha Banerjee, Subodh Samrat, Ajay Wanchu, Surjit Singh and Akhil C Banerjea

    Citation: AIDS Research and Therapy 2010 7:28

    Content type: Research

    Published on:

  38. Nef is a 27 KDa HIV-1 accessory protein. It downregulates CD4 from infected cell surface, a mechanism critical for efficient viral replication and pathogenicity. Agents that antagonize the Nef-mediated CD4 dow...

    Authors: Yong-Jiu Jin, Xiaoping Zhang, Catherine Yi Cai and Steven J Burakoff

    Citation: AIDS Research and Therapy 2010 7:26

    Content type: Research

    Published on:

  39. Recent studies have shown that the current guidelines suggesting immunologic monitoring to determine response to highly active antiretroviral therapy (HAART) are inadequate. We assessed whether routinely colle...

    Authors: Bryan Lau, Geetanjali Chander, Stephen J Gange and Richard D Moore

    Citation: AIDS Research and Therapy 2010 7:25

    Content type: Research

    Published on:

  40. Understanding co-receptor tropism of HIV-1 strains circulating in India will provide key analytical leverage for assessing the potential usefulness of newer antiretroviral drugs such as chemokine co-receptor a...

    Authors: Ujjwal Neogi, Sreenivasa B Prarthana, George D'Souza, Ayesha DeCosta, Vijesh S Kuttiatt, Udaykumar Ranga and Anita Shet

    Citation: AIDS Research and Therapy 2010 7:24

    Content type: Short report

    Published on:

  41. Stavudine continues to be widely used in resource poor settings despite its toxicity. Our objective was to determine association between plasma stavudine concentrations and lipoatrophy, concentrations of gluco...

    Authors: Phumla Z Sinxadi, Jan-Stefan van der Walt, Helen M McIlleron, Motasim Badri, Peter J Smith, Joel A Dave, Naomi S Levitt and Gary Maartens

    Citation: AIDS Research and Therapy 2010 7:23

    Content type: Research

    Published on:

  42. At present, there is no effective vaccine or other approved product for the prevention of sexually transmitted human immunodeficiency virus type 1 (HIV-1) infection. It has been reported that women in resource...

    Authors: Carol S Lackman-Smith, Beth A Snyder, Katherine M Marotte, Mark C Osterling, Marie K Mankowski, Maureen Jones, Lourdes Nieves-Duran, Nicola Richardson-Harman, James E Cummins Jr and Brigitte E Sanders-Beer

    Citation: AIDS Research and Therapy 2010 7:22

    Content type: Research

    Published on:

  43. The search for disease biomarkers within human peripheral fluids has become a favorable approach to preventative therapeutics throughout the past few years. The comparison of normal versus disease states can i...

    Authors: Rachel Van Duyne, Irene Guendel, Kylene Kehn-Hall, Rebecca Easley, Zachary Klase, Chenglong Liu, Mary Young and Fatah Kashanchi

    Citation: AIDS Research and Therapy 2010 7:21

    Content type: Research

    Published on:

  44. Long-term survival of HIV-1 infected individuals is usually achieved by continuous administration of combination antiretroviral therapy (ART). An exception to this scenario is represented by HIV-1 infected non...

    Authors: Claudia J Dembek, Sarah Kutscher, Silvia Heltai, Simone Allgayer, Priscilla Biswas, Silvia Ghezzi, Elisa Vicenzi, Dieter Hoffmann, Peter Reitmeir, Giuseppe Tambussi, Johannes R Bogner, Paolo Lusso, Hans-J Stellbrink, Elena Santagostino, Thomas Vollbrecht, Frank D Goebel…

    Citation: AIDS Research and Therapy 2010 7:20

    Content type: Research

    Published on:

  45. Although access to antiretroviral therapy (ART) for the treatment of HIV has increased during the last decade, many patients are still in need of treatment. With limited funds to provide ART to millions of pat...

    Authors: Reshmie Ramautarsing and Jintanat Ananworanich

    Citation: AIDS Research and Therapy 2010 7:18

    Content type: Review

    Published on:

  46. This report represents the first exploratory study of Chinese men who provide commercial sex services to other men ("money boys") in Jilin Province, People's Republic of China, through a convenience sample dra...

    Authors: Xiangdong Meng, Allen F Anderson, Lu Wang, Zhihe Li, Wei Guo, Zixuan Lee, Huixin Jin and Yong Cai

    Citation: AIDS Research and Therapy 2010 7:17

    Content type: Short report

    Published on: