Skip to main content

Advertisement

Articles

Page 8 of 12

  1. Hepatic Flare (HF) after initiation of highly active antiretroviral therapy (HAART) in HIV-HBV coinfected individuals is well recognized but prospective data on predictors and subsequent outcome are limited.

    Authors: Anchalee Avihingsanon, Gail V Matthews, Sharon R Lewin, Pip Marks, Jose Sasadeusz, David A Cooper, Scott Bowden, Stephen Locarnini, Greg J Dore and Kiat Ruxrungtham

    Citation: AIDS Research and Therapy 2012 9:6

    Content type: Research

    Published on:

  2. Little is known about HIV-1 subtype distribution in Morocco. Some data suggest an emergence of new HIV subtypes. We conducted phylogenetic analysis on a nationally representative sample of 60 HIV-1 viral speci...

    Authors: Mohammed Akrim, Sanae Lemrabet, Elmir Elharti, Rebecca R Gray, Jean Claude Tardy, Robert L Cook, Marco Salemi, Patrice Andre, Taj Azarian and Rajae El Aouad

    Citation: AIDS Research and Therapy 2012 9:5

    Content type: Research

    Published on:

  3. Although highly active antiretroviral therapy (HAART) has improved HIV survival, some patients receiving therapy are still dying. This analysis was conducted to identify factors associated with increased risk ...

    Authors: Alan R Lifson, Elizabeth M Krantz, Patricia L Grambsch, Grace E Macalino, Nancy F Crum-Cianflone, Anuradha Ganesan, Jason F Okulicz, Anne Eaton, John H Powers, Lynn E Eberly and Brian K Agan

    Citation: AIDS Research and Therapy 2012 9:4

    Content type: Short report

    Published on:

  4. Several lines of evidence suggest that retinoids (retinol-ROL or vitamin A, and its active metabolites, retinoic acids-RAs) play important pathogenic roles in HIV infection and combination antiretroviral thera...

    Authors: Maude Loignon, Hélène Brodeur, Sonia Deschênes, Denis Phaneuf, Pangala V Bhat and Emil Toma

    Citation: AIDS Research and Therapy 2012 9:3

    Content type: Research

    Published on:

  5. Recently, it has been shown that human ejaculate enhances human immunodeficiency virus 1 (HIV-1) infectivity. Enhancement of infectivity is conceived to be mediated by amyloid filaments from peptides that are ...

    Authors: Philip Hartjen, Sebastian Frerk, Ilona Hauber, Verena Matzat, Adriana Thomssen, Barbara Holstermann, Heinrich Hohenberg, Wolfgang Schulze, Julian Schulze zur Wiesch and Jan van Lunzen

    Citation: AIDS Research and Therapy 2012 9:2

    Content type: Research

    Published on:

  6. Use of dietary supplements is common among people living with HIV/AIDS. Because dietary supplements are used in the context of other health behaviors, they may have direct and indirect health benefits. However...

    Authors: Seth C Kalichman, Chauncey Cherry, Denise White, Miche'l Jones, Moira O Kalichman, Mervi A Detorio, Angela M Caliendo and Raymond F Schinazi

    Citation: AIDS Research and Therapy 2012 9:1

    Content type: Research

    Published on:

  7. Behaviour change which is highly influenced by risk perception is a major challenge that HIV prevention efforts need to confront. In this study, we examined the validity of self-reported likelihood of HIV infe...

    Authors: Adeniyi F Fagbamigbe, Joshua O Akinyemi, Babatunde O Adedokun and Elijah A Bamgboye

    Citation: AIDS Research and Therapy 2011 8:44

    Content type: Research

    Published on:

  8. Antiretroviral therapy (ART) requires high-level (> 95%) adherence. Kenya is rolling out ART access programmes and, issue of adherence to therapy is therefore imperative. However, published data on adherence t...

    Authors: Samwel N Wakibi, Zipporah W Ng'ang'a and Gabriel G Mbugua

    Citation: AIDS Research and Therapy 2011 8:43

    Content type: Short report

    Published on:

  9. The use of combination antiretroviral therapy (cART) has become a standard of care for the treatment of HIV infection. However, cost and resistance to cART are major obstacles for access to treatment especiall...

    Authors: Nitta Khienprasit, Romanee Chaiwarith, Thira Sirisanthana and Khuanchai Supparatpinyo

    Citation: AIDS Research and Therapy 2011 8:42

    Content type: Research

    Published on:

  10. Rifampicin reduces the plasma concentrations of nevirapine in human immunodeficiency virus (HIV) and tuberculosis (TB) co-infected patients, who are administered these drugs concomitantly. We conducted a prosp...

    Authors: Sanjeev Sinha, Sahajal Dhooria, Sanjiv Kumar, Nipam Shah, T Velpandian, AK Ravi, Narendra Kumar, Hafeez Ahmad, Akshat Bhargwa, Karan Chug, Naresh Bumma, Rahul Chandrashekhar, Meera Ekka, Vishnu Sreenivas, Surendra K Sharma, JC Samantaray…

    Citation: AIDS Research and Therapy 2011 8:41

    Content type: Research

    Published on:

  11. There are limited data of immunologic and virologic failure in Asian HIV-infected children using non-nucleoside reverse transcriptase inhibitor (NNRTI)-based highly active antiretroviral therapy (HAART). We ex...

    Authors: Torsak Bunupuradah, Thanyawee Puthanakit, Pope Kosalaraksa, Stephen Kerr, Pitch Boonrak, Wasana Prasitsuebsai, Pagakrong Lumbiganon, Tawan Mengthaisong, Chayapa Phasomsap, Chitsanu Pancharoen, Kiat Ruxrungtham and Jintanat Ananworanich

    Citation: AIDS Research and Therapy 2011 8:40

    Content type: Research

    Published on:

  12. There have been few reports of long-term survival of HIV-infected patients on antiretroviral therapy (ART) in Africa managed under near normal health service conditions.

    Authors: Barbara Amuron, Jonathan Levin, Josephine Birunghi, Geoffrey Namara, Alex Coutinho, Heiner Grosskurth and Shabbar Jaffar

    Citation: AIDS Research and Therapy 2011 8:39

    Content type: Research

    Published on:

  13. Drug resistance testing before initiation of, or during, antiretroviral therapy (ART) is not routinely performed in resource-limited settings. High levels of viral resistance circulating within the population ...

    Authors: Vijay B Bansode, Simon AA Travers, Amelia C Crampin, Bagrey Ngwira, Neil French, Judith R Glynn and Grace P McCormack

    Citation: AIDS Research and Therapy 2011 8:38

    Content type: Short report

    Published on:

  14. Partners In Health (PIH) works with the Ministry of Health to provide comprehensive health services in Haiti. Between 1994 and 2009, PIH recommended exclusive formula feeding in the prevention of mother-to-chi...

    Authors: Louise C Ivers, Sasha C Appleton, Bingxia Wang, J Gregory Jerome, Kimberly A Cullen and Mary C Smith Fawzi

    Citation: AIDS Research and Therapy 2011 8:37

    Content type: Research

    Published on:

  15. Highly effective antiviral treatment can suppress HIV-1 infection, but the chronic effects of HIV-1-related viral proteins, including gp120 and Tat, on organs such as the lungs can be damaging. HIV-1 transgeni...

    Authors: Pratibha C Joshi and David M Guidot

    Citation: AIDS Research and Therapy 2011 8:36

    Content type: Research

    Published on:

  16. CD4+ T lymphocyte counts are the most important indicator of disease progression and success of antiretroviral treatment in HIV infection in resource limited settings. The nationwide reference range of CD4+ T ...

    Authors: Madhuri R Thakar, Philip R Abraham, Sunil Arora, Pachamuthu Balakrishnan, Bhaswati Bandyopadhyay, Ameeta A Joshi, K Rekha Devi, Ravi Vasanthapuram, Madhu Vajpayee, Anita Desai, Janardhanan Mohanakrishnan, Kanwar Narain, Krishnangshu Ray, Shilpa S Patil, Ravinder Singh, Anuj Singla…

    Citation: AIDS Research and Therapy 2011 8:35

    Content type: Research

    Published on:

  17. We report an unusual case of HIV-related immune reconstitution inflammatory syndrome, presenting as suspected AIDS-related lymphoma. Symptoms, initial investigations including fine-needle biopsy and 18F-FDG PE...

    Authors: Bo K Mortensen, Susanne D Nielsen, Charlotte B Christensen and Jannik Helweg-Larsen

    Citation: AIDS Research and Therapy 2011 8:34

    Content type: Case report

    Published on:

  18. Data on lipid profile derangements induced by antiretroviral treatment in Africa are scarce. The aim of this study was to determine the prevalence and characteristics of lipid profile derangements associated w...

    Authors: Eric Walter Pefura Yone, Awa Foueudjeu Betyoumin, André Pascal Kengne, François Jérome Kaze Folefack and Jeanne Ngogang

    Citation: AIDS Research and Therapy 2011 8:33

    Content type: Research

    Published on:

  19. Effective interventions to prevent mother-to-child HIV transmission (PMTCT) exist and when properly applied reduce the risk of vertical HIV transmission. As part of optimizing PMTCT in the Dutch Caribbean we d...

    Authors: Hillegonda S Hermanides, Lonneke A van Vught, Ralph Voigt, Fred D Muskiet, Aimée Durand, Gerard van Osch, Sharline Koolman-Wever, Isaac Gerstenbluth, Colette Smit and Ashley J Duits

    Citation: AIDS Research and Therapy 2011 8:32

    Content type: Research

    Published on:

  20. We examined trends in AIDS-defining illnesses (ADIs) among individuals receiving highly active antiretroviral therapy (HAART) in British Columbia (BC), Canada to determine whether declines in ADIs could be con...

    Authors: Siavash Jafari, Keith Chan, Kewan Aboulhosn, Benita Yip, Viviane D Lima, Robert S Hogg, Julio Montaner and David M Moore

    Citation: AIDS Research and Therapy 2011 8:31

    Content type: Research

    Published on:

  21. Separately, chronic alcohol ingestion and HIV-1 infection are associated with severe skeletal muscle derangements, including atrophy and wasting, weakness, and fatigue. One prospective cohort study reported th...

    Authors: Caroline R Clary, Daniel M Guidot, Margaux A Bratina and Jeffrey S Otis

    Citation: AIDS Research and Therapy 2011 8:30

    Content type: Research

    Published on:

  22. We aimed to determine the reliability and validity of a hepatitis symptom inventory and to identify predictors of hepatitis C (HCV) treatment initiation in a cohort of HIV-infected patients.

    Authors: Edward R Cachay, David L Wyles, Miguel Goicoechea, Francesca J Torriani, Craig Ballard, Bradford Colwell, Robert G Gish and William C Mathews

    Citation: AIDS Research and Therapy 2011 8:29

    Content type: Research

    Published on:

  23. Highly Active Antiretroviral Therapy (HAART) has been available free of charge in Tanga, Tanzania since 2005. However we have found that a high percentage of women referred from prevention of mother-to-child t...

    Authors: Zahra P Theilgaard, Terese L Katzenstein, Mercy G Chiduo, Christiane Pahl, Ib C Bygbjerg, Jan Gerstoft, Martha M Lemnge and Britt P Tersbøl

    Citation: AIDS Research and Therapy 2011 8:28

    Content type: Research

    Published on:

  24. RC-101, a cationic peptide retrocyclin analog, has in vitro activity against HIV-1. Peptide drugs are commonly prone to conformational changes, oxidation and hydrolysis when exposed to excipients in a formulation...

    Authors: Alexandra B Sassi, Katherine E Bunge, Brian L Hood, Thomas P Conrads, Alexander M Cole, Phalguni Gupta and Lisa C Rohan

    Citation: AIDS Research and Therapy 2011 8:27

    Content type: Research

    Published on:

  25. Genotype-derived drug resistance profiles are a valuable asset in HIV-1 therapy decisions. Therapy decisions could be further improved, both in terms of predicting length of current therapy success and in pres...

    Authors: Glenn Lawyer, André Altmann, Alexander Thielen, Maurizio Zazzi, Anders Sönnerborg and Thomas Lengauer

    Citation: AIDS Research and Therapy 2011 8:26

    Content type: Research

    Published on:

  26. The aim of this study was to describe the extent of the HIV epidemic among women in the Republic of Georgia and to identify factors associated with HCV co-infection in this population.

    Authors: Nikoloz Chkhartishvili, Louise-Anne McNutt, Perry F Smith and Tengiz Tsertsvadze

    Citation: AIDS Research and Therapy 2011 8:25

    Content type: Research

    Published on:

  27. High early mortality rate among HIV infected patients following initiation of antiretroviral therapy (ART) in resource limited settings may indicate high pre-treatment mortality among ART-eligible patients. Th...

    Authors: Toyin Togun, Ingrid Peterson, Shabbar Jaffar, Francis Oko, Uduak Okomo, Kevin Peterson and Assan Jaye

    Citation: AIDS Research and Therapy 2011 8:24

    Content type: Research

    Published on:

  28. HAART has significantly reduced AIDS-related morbidity in children. However, limited evidence is available from developing countries regarding patterns of opportunistic illnesses. We describe these events and ...

    Authors: Alberto N Ramos Jr, Luiza H Matida, Norman Hearst and Jorg Heukelbach

    Citation: AIDS Research and Therapy 2011 8:23

    Content type: Research

    Published on:

  29. Early diagnosis of HIV infection can prevent morbidity and mortality as well as reduce HIV transmission. The aim of the present study was to assess prevalence, describe trends and identify factors associated w...

    Authors: Patricia Garcia de Olalla, Christian Manzardo, Maria A Sambeat, Inma Ocaña, Hernando Knobel, Victoria Humet, Pere Domingo, Esteve Ribera, Ana Guelar, Andres Marco, Maria J Belza, Josep M Miró and Joan A Caylà

    Citation: AIDS Research and Therapy 2011 8:22

    Content type: Research

    Published on:

  30. High dosage of intravenous immunoglobulin (IVIG) has been observed as a possible activator of HIV gene expression in latently infected resting CD4+ T-cells, leading to a substantial decrease in both the reservoir...

    Authors: Tomas Mellberg, Veronica D Gonzalez, Annica Lindkvist, Arvid Edén, Anders Sönnerborg, Johan K Sandberg, Bo Svennerholm and Magnus Gisslén

    Citation: AIDS Research and Therapy 2011 8:21

    Content type: Research

    Published on:

  31. Elite controllers (EC) are a rare subset of HIV infected individuals who control viral load below 50 copies/ml of plasma without treatment.

    Authors: Philomena Kamya, Christos M Tsoukas, Salix Boulet, Jean-Pierre Routy, Réjean Thomas, Pierre Côté, Mohamed-Rachid Boulassel, Bernard Lessard, Rupert Kaul, Mario Ostrowski, Colin Kovacs, Cecile L Tremblay and Nicole F Bernard

    Citation: AIDS Research and Therapy 2011 8:20

    Content type: Research

    Published on:

  32. Sexual behavior of HIV-positive youths, whether infected perinatally, through risky behavior or other ways, is not substantially different from that of HIV-uninfected peers. Because of highly active antiretrov...

    Authors: Nadia T Kancheva Landolt, Sudrak Lakhonphon and Jintanat Ananworanich

    Citation: AIDS Research and Therapy 2011 8:19

    Content type: Review

    Published on:

  33. To evaluate the efficacy of highly-active antiretroviral therapy (HAART) in individuals taking cytochrome P450 enzyme-inducing antiepileptics (EI-EADs), we evaluated the virologic response to HAART with or wit...

    Authors: Jason F Okulicz, Greg A Grandits, Jacqueline A French, Jomy M George, David M Simpson, Gretchen L Birbeck, Anuradha Ganesan, Amy C Weintrob, Nancy Crum-Cianflone, Tahaniyat Lalani and Michael L Landrum

    Citation: AIDS Research and Therapy 2011 8:18

    Content type: Research

    Published on:

  34. Minocycline is a tetracycline antibiotic that has been shown to attenuate central nervous system (CNS) lentivirus infection, immune activation, and brain injury in model systems. To initiate assessment of mino...

    Authors: Emily L Ho, Serena S Spudich, Evelyn Lee, Dietmar Fuchs, Elizabeth Sinclair and Richard W Price

    Citation: AIDS Research and Therapy 2011 8:17

    Content type: Research

    Published on:

  35. The potential risk of HIV-1 infection following human bite although epidemiologically insignificant, but it is biologically possible. There are anecdotal reports of HIV transmission by human bites particularly...

    Authors: Alaka K Deshpande, Shivaji K Jadhav and Atmaram H Bandivdekar

    Citation: AIDS Research and Therapy 2011 8:16

    Content type: Case report

    Published on:

  36. Our goal was to illustrate a method for making indirect treatment comparisons in the absence of head-to-head trials, by portraying the derivation of published efficacies for prophylaxis regimens of HIV-related...

    Authors: Jennifer Chu, Caroline E Sloan, Kenneth A Freedberg, Yazdan Yazdanpanah and Elena Losina

    Citation: AIDS Research and Therapy 2011 8:14

    Content type: Short report

    Published on:

  37. HIV/AIDS has orphaned 11.6 million children in sub-Saharan Africa. Expanded antiretroviral therapy (ART) use may reduce AIDS orphanhood by decreasing adult mortality and population-level HIV transmission.

    Authors: Aranka Anema, Christopher G Au-Yeung, Michel Joffres, Angela Kaida, Krisztina Vasarhelyi, Steve Kanters, Julio SG Montaner and Robert S Hogg

    Citation: AIDS Research and Therapy 2011 8:13

    Content type: Research

    Published on:

  38. The objective of this study is to identify the critical formulation parameters controlling distribution and function for the rectal administration of microbicides in humans. Four placebo formulations were desi...

    Authors: Lin Wang, Roger L Schnaare, Charlene Dezzutti, Peter A Anton and Lisa C Rohan

    Citation: AIDS Research and Therapy 2011 8:12

    Content type: Research

    Published on:

  39. Sub-Saharan Africa remains the region most heavily affected by HIV. In 2008, the region accounted for 67% of HIV infections worldwide, the region also accounted for 72% of the world's AIDS-related deaths in 20...

    Authors: Rhoune Ochako, Dunstone Ulwodi, Purity Njagi, Steven Kimetu and Aggrey Onyango

    Citation: AIDS Research and Therapy 2011 8:11

    Content type: Research

    Published on:

  40. HIV remains responsible for an estimated 40% of mortality in South African pregnant women and their children. To address these avoidable deaths, eligibility criteria for antiretroviral therapy (ART) in pregnan...

    Authors: Courtenay Sprague, Matthew F Chersich and Vivian Black

    Citation: AIDS Research and Therapy 2011 8:10

    Content type: Research

    Published on:

  41. In HIV-1 infected patients, increase of liver enzymes may be mainly due to viral coinfections, alcohol intake, hepatotoxic drugs or autoimmune diseases. Three cases of aminotransferase elevation occurred durin...

    Authors: Antonella Esposito, Valentina Conti, Maria Cagliuso, Daniele Pastori, Alessandra Fantauzzi and Ivano Mezzaroma

    Citation: AIDS Research and Therapy 2011 8:9

    Content type: Case report

    Published on:

  42. Access to free antiretroviral therapy in Sub-Saharan Africa has been steadily increasing. The success of large-scale antiretroviral therapy programs depends on early initiation of HIV/AIDs care. The purpose of...

    Authors: Yeshewas Abaynew, Amare Deribew and Kebede Deribe

    Citation: AIDS Research and Therapy 2011 8:8

    Content type: Research

    Published on:

  43. Although being considered as a rarely observed HIV-1 protease mutation in clinical isolates, the L76V-prevalence increased 1998-2008 in some European countries most likely due to the approval of Lopinavir, Amp...

    Authors: Frank Wiesmann, Jan Vachta, Robert Ehret, Hauke Walter, Rolf Kaiser, Martin Stürmer, André Tappe, Martin Däumer, Thomas Berg, Gudrun Naeth, Patrick Braun and Heribert Knechten

    Citation: AIDS Research and Therapy 2011 8:7

    Content type: Short report

    Published on:

  44. We describe two patients who did not experience a viral rebound after cessation of HAART which was initiated for progressive disease. CD4 T-cell count remained stable in one patient and progressively declined ...

    Authors: Ellen Van Gulck, Leo Heyndrickx, Lotte Bracke, Sandra Coppens, Eric Florence, Anne Buvé, Paul Lewi and Guido Vanham

    Citation: AIDS Research and Therapy 2011 8:6

    Content type: Case report

    Published on:

  45. The purpose of this study was to examine the relationship between the Medical Outcomes Study-HIV Health Survey (MOS-HIV) and the SF-12v2 to determine if the latter is adequate to assess the health-related qual...

    Authors: Allyson Ion, Wenjie Cai, Dawn Elston, Eleanor Pullenayegum, Fiona Smaill and Marek Smieja

    Citation: AIDS Research and Therapy 2011 8:5

    Content type: Research

    Published on:

  46. South Africa has a huge burden of illness due to HIV infection. Many health care workers managing HIV infected patients, particularly those in rural areas and primary care health facilities, have minimal acces...

    Authors: Briony S Chisholm, Karen Cohen, Marc Blockman, Hans-Friedemann Kinkel, Tamara J Kredo and Annoesjka M Swart

    Citation: AIDS Research and Therapy 2011 8:4

    Content type: Research

    Published on:

  47. In many preclinical AIDS research studies, antiretroviral therapy (ART) is administered to experimentally simian immunodeficiency (SIV)-infected rhesus macaques for reduction of viral load to undetectable leve...

    Authors: Brigitte E Sanders-Beer, Yvette Y Spano, Dawn Golighty, Abigail Lara, Diane Hebblewaite, Lourdes Nieves-Duran, Lowrey Rhodes and Keith G Mansfield

    Citation: AIDS Research and Therapy 2011 8:3

    Content type: Research

    Published on:

  48. Among HIV-infected persons initiating highly active antiretroviral therapy (HAART), early CD4+ lymphocyte count increases are well described. However, whether CD4+ levels continue to increase or plateau after ...

    Authors: Alan R Lifson, Elizabeth M Krantz, Lynn E Eberly, Matthew J Dolan, Vincent C Marconi, Amy C Weintrob, Nancy F Crum-Cianflone, Anuradha Ganesan, Patricia L Grambsch and Brian K Agan

    Citation: AIDS Research and Therapy 2011 8:2

    Content type: Research

    Published on:

  49. Combinatorial RNA interference (co-RNAi) approaches are needed to account for viral variability in treating HIV-1 with RNAi, as single short hairpin RNAs (shRNA) are rapidly rendered ineffective by resistant s...

    Authors: Glen J Mcintyre, Jennifer L Groneman, Yi-Hsin Yu, Anna Tran and Tanya L Applegate

    Citation: AIDS Research and Therapy 2011 8:1

    Content type: Research

    Published on: