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Table 3 Sensitivity, specificity, and positive predictive value of indications for PrEP use in the past month among a sample of transgender women in the Chicago area

From: A cross-sectional analysis of psychosocial and structural barriers and facilitators associated with PrEP use among a sample of transgender women in Chicago, IL

Past month indications for PrEP

Sensitivitya

% (95% CI)

Specificityb

% (95% CI)

1-Specificityc

% (95% CI)

PPVd

% (95% CI)

Area under the ROC curve

95% CI

Condomless vaginal/anal sex

58.3 (27.7–84.8)

52.4 (41.1–63.6)

47.6 (36.9–58.5)

15.2 (6.3–28.9)

0.55 (0.40–0.71)

Any HIV positive partners

16.7 (2.1–48.4)

93.9 (86.3–98.0)

6.1 (2.5–14.0)

28.6 (3.7–71.0)

0.55 (0.44–0.67)

STI history (ever)

41.7 (15.2–72.3)

75.6 (64.9–84.4)

24.4 (16.2–35.0)

20.0 (6.8–40.7)

0.59 (0.43–0.74)

Exchange sex

41.7 (15.2–72.3)

75.6 (64.9–84.4)

24.4 (16.2–35.0)

20.0 (6.8–40.7)

0.59 (0.43–0.74)

Combined indexe

91.7 (61.5–99.8)

41.5 (30.7–52.9)

58.5 (47.5–68.8)

18.6 (9.7–30.9)

0.67 (0.57–0.76)

Combined indexe + exchange sex

91.7 (61.5–99.8)

39.0 (28.4–50.4)

61.0 (49.4–71.0)

18.0 (9.4–30.0)

0.65 (0.56–0.75)

  1. Abbreviations: PPV, positive predictive value; ROC, receiver operating characteristic
  2. a. Proportion with PrEP indication among those on PrEP
  3. b. Proportion without PrEP indication among those not on PrEP
  4. c. Proportion with PrEP indication among those not on PrEP
  5. d. Proportion on PrEP among those with PrEP indication
  6. e. Combined index = CAS, HIV pos, STI history