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Table 2 Plasma HIV-1 suppression, total white blood and various lymphocyte counts across syphilis

From: Effects of syphilis infection among HIV-1-positive individuals on suppressive antiretroviral therapy

 

T1

T2

T3

T1 vs. T2

p-value

T2 vs. T3

p-value

CD4 + T-cell count (cells/mm3 )

559 (405–699)

519 (390–687)

562 (430–725)

0.003

< 0.001

CD8 + -cell count (cells/mm3 )

822 (621–1047)

733 (547–954)

805 (621–1044)

< 0.001

< 0.001

CD4/CD8 ratio

0.67 (0.50–0.90)

0.71 (0.52–0.95)

0.70 (0.52–0.95)

< 0.001

0.542

Plasma viral suppression, n (%)

280 (97)

282 (98)

284 (99)

0.791

0.754

Total white blood count (103 cells/µL)

5.9 (5.1–7.2)

6.2 (5.1–7.2)

6.1 (5–7.4)

0.557

0.970

Total lymphocyte count

(103cells/µL)

2.1 (1.7–2.6)

1.9 (1.6–2.4)

2.1 (1.8–2.6)

< 0.001

< 0.001

  1. Median and IQR are reported unless specified. Parameters of continuous and categorical format were compared by Wilcoxon and McNemar test, respectively. T1 = time-point before incident syphilis; T2 = time-point during syphilis; T3 = time-point after successful syphilis treatment