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Fig. 2 | AIDS Research and Therapy

Fig. 2

From: CRISPR/Cas9: a tool to eradicate HIV-1

Fig. 2

Vectors for CRISPR/Cas9 delivery. A Viral vectors include adenoviral, lentiviral and the adeno-associated viral (AAV) vectors. B Various physical and chemical methods can be used to deliver Cas9/sgRNAs. Microinjection and electroporation are mainly used in in vitro studies. The hydrodynamic tail vein injection is used for in vivo transfection of nucleic acids. Cas9/gRNAs can be delivered as RNPs via lipid-based nanoparticles like liposomes, polymeric nanocarriers and through PEI or modified PEI

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