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Fig. 1 | AIDS Research and Therapy

Fig. 1

From: Identification of CD8+ T cell subsets that normalize in early-treated people living with HIV receiving antiretroviral therapy

Fig. 1

CD8+ T cell functional features as markers of immune reconstitution in PLWH receiving cART. A PAMR estimated model accuracy and feature false discovery rate as a function of model regularization threshold from CITRUS algorithm. The green point indicates the threshold and error rate of the selected model. B Heat map showing the abundance of each cluster obtained with the model in the three groups of individuals included (HIV samples 1 and 2, and seronegative individuals’ sample 1). C Relationship of the clusters obtained with the model. The two discriminatory clusters (93 and 85) are shown in red. D Abundance and features of the two selected discriminatory clusters (93 and 85) in the three groups of individuals included (HIV samples 1 and 2, and seronegative individuals’ sample 1). E Frequencies of cluster 85 (left panel) and cluster 93 (right panel) obtained by manual flow gating in the three group of samples. P value of Dunn’s post-hoc test

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AIDS Research and Therapy

ISSN: 1742-6405

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