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Table 2 Multivariable Cox proportional hazards assessment of baseline predictors of mortality in adult patients undergoing ART

From: Comparison of predictors for early and late mortality in adults commencing HIV antiretroviral therapy in Zimbabwe: a retrospective cohort study

 

Early mortality

Late mortality

HR (95% CI)

p value

HR (95% CI)

p value

Sex (female)

1.16 (0.82, 1.63)

0.41

0.98 (0.56,1.72)

0.94

Age

1.04 (1.03, 1.06)

< 0.01

1.05 (1.02, 1.07)

< 0.01

BMI

0.95 (0.92, 0.99)

0.02

0.99 (0.94, 1.05)

0.80

Proteinuria

2.29 (1.59, 3.31)

< 0.01

2.12 (1.12, 4.01)

0.02

Diabetes mellitus

2.33 (1.10, 4.91)

0.03

3.51 (1.32, 9.32)

0.01

Hypertension

0.56 (0.33, 0.94)

0.03

0.75 (0.37, 1.51)

0.42

WHO stage I (reference)

WHO stage II

1.52 (0.93, 2.49)

0.10

1.01 (0.48, 2.12)

0.98

WHO stage III

2.05 (1.28, 3.27)

< 0.01

1.82 (0.93, 3.59)

0.08

WHO stage IV

2.83 (1.67, 4.81)

< 0.01

1.49 (0.59,3.81)

0.40

eGFR < 90 mL/min/1.73 m2

2.48 (1.56, 3.96)

< 0.01

1.29 (0.51, 3.3)

0.59

CD4 count < 50 cells/µL

1.84 (1.24, 2.72)

< 0.01

0.85 (0.37, 1.98)

0.71

  1.  h hazard ratio; CI confidence interval; BMI body mass index; eGFR estimated glomerular filtration rate