Fig. 4

Transcriptional profiles of inguinal adipose tissues of patients with HIV-1 compared to healthy controls, quantified by real-time PCR. There was a decrease in key regulatory proteins of adipocytes including PPAR-γ (peroxisome proliferator-activated receptor), adiponectin and leptin and an increase in inflammation-associated genes including PAI (plasminogen activator inhibitor)-1, HIF (hypoxia-inducible factor)-1α and TNF-α (tumor necrosis factor). GLUT1; glucose transporter 1. * p < 0.05, ** p < 0.01