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Table 2 Results of a logistic regression analysis to predict factors associated with a decrease in eGFR of more than 10 mL/min/1.73 m2 from TAF0 to TAF144

From: Renal function in Japanese HIV-1-positive patients who switch to tenofovir alafenamide fumarate after long-term tenofovir disoproxil fumarate: a single-center observational study

Variable

Odds ratio

95% confidence interval

p-value

eGFR

1.15

1.06–1.25

< 0.0001

Uβ2MG

1.00

1.00–1.00

0.77

body weight

1.14

1.02–1.27

0.01

TG

0.99

0.99–1.00

0.25

Age

1.01

0.91–1.12

0.90

Sex, male

0.13

0.00054–30.03

0.45

TDF duration

0.32

0.0027–36.98

0.63

Third agent class drug, DTG

1.02

0.099–10.58

0.99

  1. eGFR estimated glomerular filtration rate, Uβ2MG urinary β2-microglobulin, TG triglyceride, TDF tenofovir disoproxil fumarate, DTG dolutegravir
  2. Variable at TAF0
  3. Statistically significant p values are written in italics