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Table 4 Comparison of FIB-4 scores and associated indexes before and after ART in 212 patients with HIV/HBV co-infection

From: Combination antiretroviral therapy is associated with reduction in liver fibrosis scores in patients with HIV and HBV co-infection

 

ART-naive

ART

Test

P

FIB-4

2.54 ± 0.77

1.57 ± 0.23

3.899

 < 0.001

Proportion of liver fibrosis(n,%)

172(81.1)

120(56.6)

29.745

 < 0.001

ALT U/l (mean ± SD)

49 ± 6

36 ± 7

1.490

0.142

ALT > 50U/l (n,%)

64(30.2)

28(13.2)

17.991

 < 0.001

AST U/l (mean ± SD)

68 ± 8

37 ± 4

4.095

 < 0.001

AST > 40U/l (n,%)

120(56.6)

52(24.5)

45.233

 < 0.001

PLT < 100(× 109/l) (mean ± SD)

133 ± 9

191 ± 12

-4.816

 < 0.001

PLT < 100(× 109/l) (n,%)

64(30.2)

20(9.4)

28.742

 < 0.001