Table 3 Incidence of liver fibrosis by different risk factors in patients with HIV/HBV co-infection
Group | Number | No. of liver fibrosis (%) | X2 | P | Relative risk (95% CI) |
|---|---|---|---|---|---|
≥ 45 Years | 264 | 202(76.5) | 42.534 | < 0.001 | 3.688(2.470–5.505) |
< 45 Years | 194 | 91(46.9) | |||
HBeAg(-) | 358 | 242(67.6) | 9.343 | 0.002 | 2.004(1.278–3.144) |
HBeAg( +) | 100 | 51(51.0) | |||
Detectable HIV-RNA | 176 | 129(73.3) | 10.777 | 0.001 | 1.975(1.312–2.973) |
Unetectable HIV-RNA | 282 | 164(58.2) | |||
ART-naive | 148 | 109(73.6) | 8.880 | 0.003 | 1.914(1.245–2.943) |
ART | 310 | 184(59.4) | |||
CD4 ≤ 200/ul | 322 | 236(73.3) | 40.853 | < 0.001 | 3.803(2.497–5.792) |
CD4 > 200/ul | 136 | 57(41.9) | |||
ALT > 50U/l | 89 | 78(87.6) | 26.846 | < 0.001 | 5.079(2.614–9.869) |
Normal ALT | 369 | 215(58.3) | |||
AST > 40U/l | 149 | 134(89.9) | 64.573 | < 0.001 | 8.428(4.726–15.028) |
Normal AST | 309 | 159(51.5) | |||
PLT < 100(× 109/l) | 121 | 110(90.9) | 51.766 | < 0.001 | 8.415(4.368–16.214) |
Normal PLT | 337 | 183(54.3) |