Table 2 Risk factors associated with liver fibrosis (FIB-4) in patients with HIV/HBV co-infection
Univariate | Multivariate | |||
|---|---|---|---|---|
P | OR(95% CI) | P | OR(95% CI) | |
Male | 0.706 | 0.912(0.565–1.473) | ||
≥ 45 years | 0.000 | 4.103(2.726–6.174) | 0.000 | 7.194(3.259–15.884) |
HCV co-infection | 0.038 | 2.149(1.042–4.430) | 0.147 | 3.155(0.668–14.899) |
HBsAg < 50 | 0.201 | 0.673(0.366–1.236) | ||
HBeAg positive | 0.002 | 2.075(1.314–3.279) | 0.009 | 0.158(0.040–0.634) |
HBeAb positive | 0.003 | 2.044(1.280–3.262) | 0.569 | 1.402(0.438–4.484) |
Detectable HBV-DNA | 0.001 | 2.201(1.404–3.451) | 0.309 | 1.759(0.592–5.225) |
Detectable HIV-RNA | 0.001 | 2.081(1.337–3.239) | 0.000 | 27.850(1.607–81.401) |
ART | 0.005 | 0.532(0.341–0.829) | 0.000 | 0.016(0.009–0.136) |
CD4 > 200/ul | 0.000 | 0.300(0.188–0.479) | 0.012 | 0.336(0.144–0.786) |
ALT > 50 U/l | 0.005 | 3.929(1.508–10.242) | 0.046 | 20.488(1.012–60.190) |
AST > 40 U/l | 0.000 | 20.941(5.054–86.773) | 0.026 | 27.323(1.478–55.122) |
PLT < 100(× 109/l) | 0.000 | 13.901(4.351–75.232) | 0.000 | 61.246(7.361–109.604) |