Table 4 The results of subgroup meta-analysis by study regions and time period
| Â | Pooled OR (95%CI) | P-value | Pooled OR (95%CI) | P-value | Publication bias | ||
|---|---|---|---|---|---|---|---|
High prevalence regions | Middle or low prevalence regions |  | 2010–2015 | 2016–2020 |  | P-value | |
Age | 1.67 (1.35–2.07) | 2.50 (2.04–3.05) | 0.01* | 2.48 (1.77–3.49) | 1.79 (1.43–2.25) | 0.12 | 0.4632 |
Gender | 1.22 (1.00–1.48) | 0.94 (0.81–1.08) | 0.04* | 0.80 (0.63–1.02) | 1.11 (0.88–1.41) | 0.06 | 0.6793 |
Marital status | 1.18 (1.00–1.38) | 1.65 (1.46–1.87) |  < 0.01* | 1.81 (1.45–2.26) | 0.94 (0.78–1.14) |  < 0.01* | 0.814 |
Infection routes | 2.08 (1.57–2.74) | 1.87 (1.70–2.06) | 0.49 | 2.13 (1.77-2.57) | 1.43( 0.94–2.17) | 0.09 | 0.1438 |
Sample sources | 1.89 (1.58–2.26) | 2.57 (2.28–2.89) | 0.01* | 3.00 (2.52–3.58) | 1.57 (1.24–1.99) |  < 0.01* | 0.3912 |