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Table 1 Stages of HIV markers/ diagnostic tests in early infection, as described by Fiebig et al.

From: Acute HIV infection syndrome mimicking COVID-19 vaccination side effects: a case report

Fiebig stage

HIV-PCR

4th-generation screening test

Western blot

p24- antigen

Antibodies

Days since infection

Eclipse

 − 

 − 

 − 

 − 

 − 

0–11

I

 + 

 − 

 − 

 − 

 − 

12–16

II

 + 

 + 

 − 

 + 

 − 

17–21

III

 + 

 + 

 − 

 + 

HIV-IgM: + 

22–24

IV

 + 

 + 

inconclusive

 + / − 

2/3 antibodies positive (p24, gp41, gp120)

25–30

V

 + 

 + 

 + 

 + / − 

3/3 antibodies positive (p24, gp41, gp120) lacking p31

31–100

VI

 + 

 + 

 + 

 + / − 

3/3 antibodies positive (p24, gp41, gp120), p31-antibodies positive

Open-ended

  1. The table is as described by Fiebig et al., modified after [1, 4, 5]. Results of diagnostic tests (HIV-PCR, fourth-generation screening tests, Western blot) and detectability of HIV markers (p24-antigen, HIV-specific antibodies) are shown in relation to days since infection. (+) indicates positive test result/ detectability, (−) indicates negative test result/ HIV-marker not detectable. Eclipse and Fiebig stages are listed in dependence of HIV-marker, as described by Fiebig et al.