Table 2 Median years of exposure and number of acute myocardial infarction (AMI) events occurring over total person-time of exposure to combinations of anti-retroviral agents
Antiretroviral drug | Median no. of years of exposure (IQR) | No. of AMI events | Person years of exposure | Incidence rate per 1000 people (95% CI) |
|---|---|---|---|---|
ABC-3TC-ATV | 2.75 (1.58, 4.17) | 30 | 3951 | 7.6 (5.3–8.7) |
ABC-3TC-DRV | 2.83 (1.58, 4.08) | 26 | 2395 | 11.0 (7.4–16) |
ABC-3TC-ZDV | 2.92 (1.75, 4.33) | 19 | 2882 | 6.6 (4.2–10.3) |
ABC-3TC-EFV | 2.92 (1.75, 4.25) | 9 | 2541 | 3.5 (1.8–6.8) |
ABC-3TC-RAL | 3.08 (1.75, 4.12) | 20 | 3055 | 6.5 (4.2–10.1) |
TDF-3TC-ZDV | 3.58 (2.25, 4.67) | 32 | 5549 | 5.8 (4.1–8.2) |
TDF-3TC-EFV | 3.58 (2.33, 4.58) | 18 | 4529 | 4.1 (2.5–6.3) |
TDF-3TC-DRV | 3.16 (2.00, 4.33) | 19 | 2336 | 8.1 (5.2–12.8) |
TDF-3TC-ATV | 3.25 (1.92, 4.42) | 23 | 2843 | 8.1 (5.4–12.2) |
TDF-FTC-ATV | 2·83 (1.67, 4.17) | 63 | 13,620 | 4.6 (3.6–5.9) |
TDF-FTC-DRV | 2·67 (1.50, 4.83) | 62 | 10,981 | 5.6 (4.4–7.2) |
TDF-FTC-EFV | 2·92 (1.75, 4.33) | 170 | 49,493 | 3.4 (3.0–4.0) |
TDF-FTC-FPV | 3·17 (1.83, 4.42) | 13 | 2465 | 5.3 (3.1–9.1) |
TDF-FTC-RAL | 2·83 (1.67, 4.17) | 92 | 13,729 | 6.7 (5.5–8.2) |