Table 1 Baseline characteristics of adults with HIV infection, with and without acute myocardial infarction (AMI) receiving antiretroviral therapy in the Pharmetrics Plus data from October 2009 through December 2014 in the United States
Characteristics | All patients (N = 73,071), n (%) | Patients without AMI (N = 72,469), n (%) | Patients with AMI (N = 602), n (%) |
|---|---|---|---|
Age, median (IQR) | 45 (38–52) | 45 (38–52) | 53 (48–59) |
Male gender | 59,514 (81.4) | 58,981 (81.4) | 533 (88.5) |
Region | |||
 East | 17,523 (24.0) | 17,354 (24.0) | 169 (28.1) |
 Mid-West | 13,532 (18.5) | 13,411 (18.5) | 121 (20.1) |
 South | 33,271 (45.5) | 33,014 (45.6) | 257 (42.7) |
 West | 8745 (12.0) | 8690 (12.0) | 55 (9.1) |
Year of ART initiation | |||
 2009 | 24,435 (33.4) | 24,127 (33.3) | 308 (51.2) |
 2010 | 9729 (13.3) | 9636 (13.3) | 93 (15.5) |
 2011 | 10,274 (14.1) | 10,190 (14.1) | 84 (14.0) |
 2012 | 8605 (11.8) | 8559 (11.8) | 46 (7.6) |
 2013 | 7830 (10.7) | 7794 (10.8) | 36 (6.0) |
 2014 | 12,198 (16.7) | 12,163 (16.8) | 35 (5.8) |
Ever substance abuse | 13,395 (18.3) | 13,152 (18.2) | 243 (40.4) |
Ever alcohol abuse | 3093 (4.2) | 3039 (4.2) | 54 (9.0) |
Ever tobacco use | 11,849 (16.2) | 11,587 (16.0) | 262 (43.5) |
Body mass index > 24.9 | 1511 (2.07) | 1503 (2.07) | 8 (1.33) |
Essential hypertension | 7450 (10.2) | 7336 (10.1) | 114 (19.0) |
Diabetes mellitus or receipt of anti-hyperglycemic agentsa | 4128 (5.7) | 4052 (5.6) | 76 (12.6) |
Chronic Kidney Disease | 729 (1.0) | 701 (1.0) | 28 (4.7) |
Dyslipidemia | 8616 (11.8) | 8496 (11.7) | 120 (19.9) |
Lipodystrophy | 224 (0.3) | 220 (0.3) | 4 (0.7) |
Pre-existing heart diseaseb | 1754 (2.4) | 1688 (2.3) | 66 (11.0) |
Receipt of medications for heart diseasec | 14,336 (19.6) | 14,074 (19.4) | 262 (43.5) |
History of stroke | 211 (0.3) | 204 (0.3) | 7 (1.2) |
Hepatitis B | 959 (1.3) | 953 (1.3) | 6 (1.0) |
Hepatitis C | 1520 (2.1) | 1500 (2.1) | 20 (3.3) |
History of cancer | 5499 (7.5) | 5442 (7.5) | 57 (9.5) |