Skip to main content

Table 2 Associations between baseline variables and mental health problems at Month 12 (among those who completed all three surveys: baseline, Month 6, and Month 12, n = 300)

From: Associations between antiretroviral therapy-related experiences and mental health status among people living with HIV in China: a prospective observational cohort study

Variables

Probable depression

Moderate/severe anxiety

Row%

ORu (95% CI)

Row%

ORu (95% CI)

Background characteristics

 Age (years)

  18–

16.9

1.00

13.8

1.00

  25–

9.8

0.53 (0.22, 1.28)

5.3

0.35 (0.12, 0.97)*

  35–

17.1

1.02 (0.41, 2.53)

11.4

0.80 (0.28, 2.24)

  45–

18.8

1.13 (0.36, 3.33)

6.2

0.41 (0.06, 1.74)

 Sex

  Female

36.8

1.00

21.1

1.00

  Male

12.5

0.24 (0.09, 0.69)**

7.8

0.32 (0.10, 1.19)†

 Education

  Primary school and below

16.5

1.00

8.8

1.00

  Junior or senior high

14.6

0.87 (0.37, 1.98)

13.4

1.61 (0.62, 4.36)

  College and above

11.8

0.68 (0.31, 1.48)

5.5

0.61 (0.20, 1.75)

 Current marital status

  Married or cohabiting with a partner

14.4

1.00

10.6

1.00

  Single

14.4

1.00 (0.50, 2.04)

7.8

0.71 (0.31, 1.69)

  Other

10.3

0.68 (0.15, 2.28)

6.9

0.63 (0.09, 2.52)

 Monthly personal income in RMB (USD)

  No fixed income

18.0

1.00

14.0

1.00

  < 3000 (< 433 USD)

17.1

0.94 (0.37, 2.50)

12.9

0.91 (0.31, 2.71)

  3000-(433-USD)

14.8

0.79 (0.33, 2.01)

7.4

0.49 (0.17, 1.48)

  5000-(722-USD)

6.9

0.34 (0.10, 1.05)†

2.8

0.18 (0.03, 0.77)*

 Employment status

  Full-time

13.0

1.00

7.9

1.00

  Part-time/unemployed/retired/student

15.4

1.22 (0.63, 2.36)

9.8

1.26 (0.55, 2.83)

 City of permanent residence

  Guangzhou

8.7

1.00

5.8

1.00

  Other cities

15.6

1.94 (0.83, 5.3)

9.5

1.71 (0.63, 6.01)

HIV/AIDS-related characteristics

 Presence of AIDS-related symptoms

  No

14.8

1.00

9.5

1.00

  Yes

12.6

0.83 (0.41, 1.64)

7.2

0.74 (0.29, 1.71)

 CD4 cell count (cell/mm3)

  < 200

12.8

1.00

10.3

1.00

  200–

15.6

1.25 (0.57, 2.92)

8.9

0.85 (0.34, 2.27)

  350–

10.2

0.77 (0.25, 2.21)

6.8

0.64 (0.16, 2.13)

  500–

17.9

1.48 (0.42, 4.63)

7.1

0.67 (0.10, 2.90)

 Route of HIV transmission

  Sexual behavior with same-sex partner

12.0

1.00

8.4

1.00

  Sexual behavior with opposite-sex partner

15.3

1.31 (0.55, 2.94)

6.8

0.80 (0.22, 2.28)

  Other routes#

14.3

1.22 (0.18, 4.84)

7.1

0.84 (0.04, 4.66)

  Not sure

22.2

2.09 (0.81, 4.98)

13.9

1.76 (0.55, 4.88)

 ART regimen

  Tenofovir, lamivudine, and efavirenz

13.7

1.00

8.2

1.00

  Other

15.6

1.16 (0.45, 2.66)

11.1

1.39 (0.45, 3.65)

Psychosocial status

 Social support (\(\overline{x} \pm {\text{s}}\)) (range 1–7)

  Family

N.A

0.98 (0.79, 1.24)

N.A

0.83 (0.64, 1.09)

  Friends

N.A

0.71 (0.57, 0.90)**

N.A

0.61 (0.46, 0.81)***

  Significant others

N.A

0.71 (0.55, 0.91)**

N.A

0.76 (0.56, 1.03)†

Social stigma (\(\overline{x} \pm {\text{s}}\)) (range 13–52)

N.A

1.06 (1.01, 1.12)*

N.A

1.08 (1.02, 1.15)**

Mental health problems

 Probable depression (PHQ-9 score ≥ 10)

30.4

4.37 (2.21, 8.69)***

14.5

2.28 (0.95, 5.22)†

 Moderate/severe anxiety (GAD-7 score ≥ 10)

25.0

2.42 (1.07, 5.17)*

15.9

2.36 (0.87, 5.79)†

  1. N.A. Not applicable
  2. #Intravenous drug use, mother-to-child transmission, blood transfusion, occupational exposure
  3. † 0.05 < P < 0.1; * P < 0.05; ** P < 0.01; *** P < 0.001