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Table 4 Hazard ratios from the single variable and multivariable analysis of the association between the possible predictors of mortality

From: Predictors of mortality rate among adult HIV-positive patients on antiretroviral therapy in Metema Hospital, Northwest Ethiopia: a retrospective follow-up study

Independent variables

CHR (95% CI)

AHR (95% CI)

Age in years

 15–24

1.00

1.00

 25–34

0.99 (0.43–2.27)

0.70 (0.25–1.92)

 35–44

1.51 (0.65–3.50)

1.11 (0.37–3.31)

 ≥ 45

2.29 (0.99–5.31)

2.43 (0.81–7.31)

Sex

 Female

1.00

1.00

 Male

2.10 (1.35–3.27)

2.40 (1.24–4.62)***

Education level

 No education

1.94 (0.96–3.90)

0.68 (0.26–1.79)

 Primary

1.10 (0.48–2.52)

0.59 (0.19–1.82)

 Secondary & above

1.00

1.00

Hemoglobin

 Low

5.73 (3.71–8.85)

4.14 (2.18–7.86)***

 Normal

1.00

1.00

Viral load

 ≤ 1000

1.00

1.00

 > 1000

9.84 (5.78–16.73)

6.70 (3.40–13.22)***

CD4

 ≤ 200

6.90 (3.87–12.31)

1.71 (0.77–3.76)

 201–350

0.89 (0.36–2.20)

0.53 (0.16–1.76)

 > 351

1.00

1.00

TB coinfection

 Yes

5.24 (3.04–9.05)

3.71 (1.59-8.64)***

 No

1.00

1.00

BMI in kg/m2

 ≥ 18.5

1.00

1.00

 15.5–18.4

1.88 (1.15–3.09)

1.07 (0.51–2.22)

 ≤ 15.4

2.43 (1.41–4.20)

2.45 (1.17–5.10)***

WHO clinical stage

 Stage I

1.00

1.00

 Stage II

3.92 (1.84–8.34)

2.58 (0.94–7.07)

 Stage III

3.63 (1.82–7.24)

3.31 (1.35–8.10)***

 Stage IV

6.52 (3.46–12.30)

5.64 (2.53–12.56)***

Functional status

 Working

1.00

1.00

 Ambulatory

3.57 (2.04–6.23)

1.04 (0.48–2.24)

 Bedridden

4.40 (2.70–7.18)

0.93 (0.45–1.94)

Adherence

 Good

1.00

1.00

 Fair

0.27 (0.08–0.86)

0.38 (0.08–1.70)

 Poor

1.37 (0.77–2.43)

0.92 (0.40–2.09)

Disclosure status

 Yes

1.00

1.00

 No

1.43 (0.93–2.19)

0.84 (0.45–1.58)

OIs other than TB

 Yes

3.41 (2.16–5.39)

1.19 (0.55–2.55)

 No

1.00

1.00

Occupation

 Merchant

1.00

1.00

 Daily laborer

8.86 (2.15–36.54)

5.57 (0.71–43.94)

 Farmer

5.97 (1.39–25.53)

3.81 (0.45–32.01)

 Housewife

4.90 (1.12–21.44)

5.74 (0.68–48.23)

 Othersa

2.62 (0.37–18.56)

0.45 (0.02–9.14)

  1. HR: Hazard ratio; CI: Confidence interval; OIs: Opportunistic infection; 1: reference; BMI: body mass index
  2. ***Indicates that the variables significantly associated with the outcome at a 95% level of significance (P < 0.005)
  3. aIndicates that driver, students, and jobless