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Table 1 Summary of the pooled efficacy outcome

From: Integrase inhibitors versus efavirenz combination antiretroviral therapies for TB/HIV coinfection: a meta-analysis of randomized controlled trials

Outcome or subgroup

Studies

Cases

No. with event/total no. of patients

INIs and EFV

Effect estimate (RR and 95% CI)

Virologic suppression

3

672

231/350 and 223/322

0.94 (0.85,1.05)

 DTG vs. EFV

1

113

52/69 and 36/44

0.92 (0.76,1.12)

 RAL vs. EFV

2

559

179/281 and 187/278

0.95 (0.84,1.07)

Bacteriology suppression

3

672

313/350 and 288/322

1.00 (0.95,1.05)

 DTG vs. EFV

1

113

61/69 and 40/44

0.97 (0.86,1.10)

 RAL vs. EFV

2

559

252/281 and 248/278

1.01 (0.95,1.06)

Adherence

3

617

309/321 and 291/296

0.98 (0.95,1.01)

 DTG vs. EFV

1

99

56/58 and 38/41

1.04 (0.94,1.15)

 RAL vs. EFV

2

518

253/263 and 253/255

0.97 (0.94,1.00)