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Table 2 A gender-based comparison of descriptive study characteristics

From: Predictors of failure on second-line antiretroviral therapy with protease inhibitor mutations in Uganda

Characteristic

Females

Males

Controls

Cases

Total

Controls

Cases

Total

n (col %)

n (col %)

n (col %)

n (col %)

n (col %)

n (col %)

Type of Second-line drug

Alluvia

143(94.7)

25(89.3)

168(93.9)

98(94.2)

46(80.7)

144(89.4)

Atazanavir

5(3.3)

3(10.7)

8(4.5)

3(2.9)

1(1.8)

4(2.5)

Other PIµ

3(2.0)

0(0)

3(1.7)

3(2.9)

10(17.5)

13(8.1)

Total

151(100)

28(100)

179(100)

104(100)

57(100)

161(100)

TB treatment ψ

No

146(97.3)

23(82.1)

169(94.9)

100(97.1)

48(84.2)

148(92.5)

Yes

4(2.7)

5(17.9)

9(5.1)

3(2.9)

9(15.8)

12(7.5)

Total

150(100)

28(100)

178(100)

103(100)

57(100)

160(100)

Year of ART initiation

Before 2001

6(4.0)

2(7.1)

8(4.5)

1(1.0)

21(36.8)

22(13.7)

2001–2005

91(60.3)

15(53.6)

106(59.2)

79(76.0)

26(45.6)

105(65.2)

2006–2010

44(29.1)

9(32.1)

53(29.6)

20(19.2)

10(17.5)

30(18.6)

2011–2015

10(6.6)

2(7.1)

12(6.7)

4(3.8)

0 (0)

4(2.5)

Total

150(100)

28(100)

179(100)

104(100)

57(100)

161(100)

Type of First-line drug

NNRTI based

129(85.4)

22(78.6)

151(84.4)

88(84.6)

44(77.2)

132(82.0)

NON-NNRTI

22(14.6)

6(21.4)

28(15.6)

16(15.4)

13(22.8)

29(18.0)

Total

151(100)

28(100)

179(100)

104(100)

57(100)

161(100)

Other comorbidities§

No

139(93.3)

28(100)

167(94.4)

87(83.7)

48(84.2)

135(83.9)

Yes

10(6.7)

0(0)

10(5.6)

17(16.3)

9(15.8)

26(16.1)

Total

149(100)

28(100)

177(100)

104(100)

57(100)

161(100)

No

139(93.3)

28(100)

167(94.4)

87(83.7)

48(84.2)

135(83.9)

Yes

10(6.7)

0(0)

10(5.6)

17(16.3)

9(15.8)

26(16.1)

Total

149(100)

28(100)

177(100)

104(100)

57(100)

161(100)

Age at the start of 2nd line ART: median (IQR)

36 (31–41)

35.5(31.5–38)

36(31–41)

43(35–49)

39(31–48)

42(33–49)

CD4 at the start of 2nd line ART: median (IQR)

155(77–253)

65.5(15–135)

137(62–243)

101.5(37–230)

78.5(28.5–205)

93(34–205)

VL at start of 2nd line ART: median (IQR)¥

37,706(12,880–135,248)

233,700(51,014–547,922)

50,305.5(1453.5–162,197)

54,588(14,444–135,859)

139,901(72,510–645,978)

76,115(21,919.5–250,702)

Duration on 1st line: median (IQR)

4(2–5)

3(1.5–4)

3(2–5)

3(2–5)

4(2–6)

3(2–6)

  1. §Missing data on two observations, ψ Missing data on one observation, ¥ Missing data on 128 observations, TB: tuberculosis, VL: Viral Load, IQR: Interquartile Range, ART: Antiretroviral Therapy, ∞Non-NRTI: triple nucleosides, µ “other PI”: saquinavir and nelfinavir