Table 2 Factors associated with loss to follow up among patients initiated on second-line ART at MRRH HIV Clinic
Characteristic | Active n (%) | LTFU n (%) | Unadjusted risk ratio [C I] | p values | Adjusted Risk Ratios [C.I] | p values |
|---|---|---|---|---|---|---|
Male gender | 324 (79.8) | 82 (20.2) | 1.1 [1.02–1.2] | 0.01 | 1.8 [1.5–2.0] |  < 0.001 |
Age categories | ||||||
 18–24 | 52 (77.6) | 15 (33.4) | 1 |  |  |  |
 25–34 | 225 (82.7) | 47 (17.3) | 0.9 [0.8–1.1] | 0.43 | ||
 35–49 | 398 (83.6) | 78 (16.4) | 0.9 [0.7–1.1] | 0.19 | ||
  ≥ 50 | 80 (73.4) | 29 (26.1) | 1.3 [1.2–1.6] |  < 0.001 | ||
Patient category | ||||||
 Original cohort | 587 (86.1) | 95 (13.9) | 1 |  |  |  |
 Transfer in | 168 (69.4) | 74 (30.6) | 1.9 [1.8–2.1] |  < 0.001 | 0.9 [0.8–1.2] | 0.62 |
CD4 categories | ||||||
 < 100 | 371 (85.7) | 62 (14.3) | 1 |  |  |  |
 100–250 | 219 (85.6) | 37 (14.4) | 1 [0.9–1.41] | 0.63 | ||
 251–500 | 86 (86) | 14 (14) | 1 [0.9–1.3] | 0.38 | ||
 > 500 | 35 (92.1) | 3 (7.9) | 0.4 [0.3–0.6] |  < 0.001 | ||
Body-mass index Underweight | ||||||
 Normal BMI | 115 (78.8) | 31 (21.2) | 1 |  |  |  |
 Overweight | 390 (87.8) | 54 (12.2) | 0.6 [0.5–0.7] |  < 0.01 | 0.8 [0.7–1.0] | 0.03 |
 Obese | 59 (90.8) | 6 (9.2) | 0.4 [0.3–0.5] |  < 0.01 | 0.7 [0.5–1.0] | 0.03 |
|  | 25 (86.2) | 4 (13.8) | 0.3 [0.2–0.6] |  < 0.01 | 0.2 [0.05–0.5] | 0.001 |
Viral load | ||||||
  < 1000 | 12 (80) | 3 (20) | 1 |  |  |  |
 > 1000 | 390 (91.2) | 39 (8.8) | 0.4 [0.3–0.5] |  < 0.001 |  |  |
Hemoglobin | ||||||
 No Anemia | 422 (88.7) | 54 (11.3) | 1 |  |  |  |
 Mild Anemia | 138 (85.2) | 24 (14.8) | 1.3 [1.1–1.5] |  < 0.001 | 1.4 [1.1–1.6] |  < 0.001 |
 Moderate- Severe Anemia | 111 (81) | 26 (19) | 1.8 (1.5–2.0) |  < 0.001 | 1.4 [1.1–1.7] |  < 0.001 |
Marital status | ||||||
 Married | 342 (80.1) | 82 (19.3) | 1 |  |  |  |
 Single/widowed/ | 364 (82.3) | 78 (17.7) | 0.9 (09–1.1) | 0.84 |  |  |
 Divorced |  |  |  |  |  |  |
HIV staging | ||||||
 1 | 334 (87.4) | 48 (12.6) | 1 |  | 1 |  |
 2 | 152 (85.9) | 25 (14.1) | 1.1 [0.6–1.5] | 0.09 | 1.2 [1.0–1.4] | 0.04 |
 3 | 165 (84.6) | 30 (15.4) | 1.2 [1.1–1.4] | 0.06 | 0.9 [0.7–1.1] | 0.22 |
 4 | 91 (79.8) | 23 (20.2) | 1.3 [1.1–1.5] |  < 0.01 | 0.7 [0.5–1.0] | 0.03 |
Year of Starting ART | ||||||
 Before 2006 | 351 (79.1) | 93 (20.9) | 1 |  |  |  |
 2006 to 2010 | 233 (83.8) | 45 (16.2) | 0.6 [0.5–0.7] |  < 0.001 | 3.9 [2.9–5.3] |  < 0.001 |
 2011 on wards | 155 (87.1) | 23 (12.9) | 0.6 [0.5–0.7] |  < 0.001 | 2.2 [1.7–3.0] |  < 0.001 |
History of Kaposi | ||||||
 Sarcoma | 26 (78.8) | 7 (21.2) | 1.1 [0.9–21.5] | 0.2 |  |  |
 History of Tuberculosis | 60 (82.2) | 13 (17.8) | 0.91 [0.7–1.0] | 0.14 |  |  |
 Switched due to Clinical Failurea | 182 (71.1) | 74 (28.9) | 2.2 (2.1–2.4) |  < 0.00 |  |  |