Table 1 Sociodemographic, clinical and laboratory characteristics at the start of second line ART
Characteristic, N = 924 | Missing n (%) |  |
|---|---|---|
Age in years, mean (SD) | – | 38.4 ±  (10.5) |
Female gender n (%) | – | 518 (56.1) |
Transfer in | – | 242 (26.2) |
Baseline CD4 cells/mm3 median (IQR) | 97 (10) | 95 (48–195) |
Baseline CD4 categories | ||
 < 100 | 97 (10) | 433 (52.4) |
 100–250 |  | 256 (31) |
 251–500 |  | 100 (12.1) |
 > 500 |  | 38 (4.6) |
BMI in kg/m2 mean (SD) | 240 (25.9) | 21.6 (4.4) |
Viral load (copies/ml) median (IQR) | 483 (52.3) | 35,500 (11,294–1,189,000) |
Baseline lymphocyte count median (IQR) | 310 (33.6) | 1.2 (1–1.9) |
Baseline Hemoglobin (g/dl), mean ±  (SD) | 149 (16.1) | 12.8 ± 2.1 |
Switch criteria n (%) | ||
Clinical failure | 96 (10.4) | 256 (30.9) |
 Immunological failure |  | 307 (37.1) |
 Virological failure |  | 264 (31.9) |
Marital status n (%) | ||
 Single | 58 (6) | 424 (49) |
 Married |  | 442 (51) |
 Employed n (%) | 74 (8) | 753 (81.8) |
Self-reported Poor Adherence status, n (%) | – | 799 (86.5) |
Alcohol Intake, n (%) | 482 (52.2) | Â |
 Yes |  | 119 (24.7) |
 No |  | 363 (75.3) |
First Line ART Backbone, n (%) | Â | Â |
D4T or DDI based | Â | 357 (38.8) |
AZT and3TC based | Â | 418 (45.4) |
3TC and TDF | - | 146 (15.8) |
Firstline ART Start Year | ||
 < 2006 | 24 | 444 (49.3) |
 2006–2010 |  | 278 (30.9) |
 > 2010 |  | 178 (19.8) |
History of opportunistic infections | ||
 Kaposi’s Sarcoma |  | 33 (28.1) |
 Cryptococcal meningitis |  | 10 (8.7) |
 Tuberculosis | – | 73 (63.2) |
HIV staging | ||
 1 | 56 (6.1) | 382 (44) |
 2 |  | 177 (20.4) |
 3 |  | 195 (22.5) |
 4 |  | 114 (13.1) |