TY - JOUR AU - Bessong, Pascal O. AU - Matume, Nontokozo D. AU - Tebit, Denis M. PY - 2021 DA - 2021/01/06 TI - Potential challenges to sustained viral load suppression in the HIV treatment programme in South Africa: a narrative overview JO - AIDS Research and Therapy SP - 1 VL - 18 IS - 1 AB - South Africa, with one of the highest HIV prevalences in the world, introduced the universal test and treat (UTT) programme in September 2016. Barriers to sustained viral suppression may include drug resistance in the pre-treated population, non-adherence, acquired resistance; pharmacokinetics and pharmacodynamics, and concurrent use of alternative treatments. SN - 1742-6405 UR - https://doi.org/10.1186/s12981-020-00324-w DO - 10.1186/s12981-020-00324-w ID - Bessong2021 ER -