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Table 2 Unadjusted and Adjusted Change in CD4 for participants < 50 and ≥ 50 years by time since ART initiation

From: Impact of age on CD4 recovery and viral suppression over time among adults living with HIV who initiated antiretroviral therapy in the African Cohort Study

 

Unadjusted change in CD4

Adjusted change in CD4a

Average CD4

95% CI

Average CD4

95% CI

Constant

306

283–330

282

218–345

Age ≥ 50

52

− 38–142

37

− 58–132

Time

 6 months

128

108–148

146

124–166

 12 months

156

135–178

174

150–199

 18 months

176

153–199

192

166–217

 24 months

188

163–214

203

174–231

 30 months

217

185–248

230

197–263

 36 months

195

162–228

213

179–247

 42 months

199

161–237

289

225–353

Age*visit interaction

 Age ≥ 50* 6 months

− 20

− 66–26

− 3

− 62–55

 Age ≥ 50* 12 months

− 48

− 101–4

− 29

− 96–38

 Age ≥ 50* 18 months

− 35

− 100–29

− 22

− 95–51

 Age ≥ 50* 24 months

47

− 41–135

66

− 28–162

 Age ≥ 50* 30 months

− 38

− 129–54

− 11

− 106–84

 Age ≥ 50* 36 months

− 71

− 182–40

− 52

− 159–55

 Age ≥ 50* 42 months

− 147

− 263–31

− 130

− 377–116

  1. aAdjusted for study site, education, gender, dysglycemia and hypercholesterolemia