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Table 3 Univariate and multivariate analysis of predictors of virological failure

From: Predictors of first-line antiretroviral therapy failure among adults and adolescents living with HIV/AIDS in a large prevention and treatment program in Nigeria

Characteristics

Unadjusted

RR PR (95% CI)

p-value1

Adjusted

PRR (95% CI)

p-value2

Age categories

 < 30

1.00

 

1.00

 

 30–39

0.57 (0.42–0.77)

< 0.001

0.45 (0.31–0.67)

< 0.001

 40–49

0.56 (0.41–0.76)

< 0.001

0.42 (0.28–0.63)

< 0.001

 50 +

0.37 (0.26–0.54)

< 0.001

0.23 (0.14–0.39)

< 0.001

Marital status

 Married

0.73 (0.60–0.91)

0.004

0.71 (0.55–0.97)

0.021

 Others

1.00

 

.00

 

Service entry point

 Voluntary counseling and testing

1.61 (1.25–2.07)

< 0.001

1.45 (1.11–1.91)

0.007

 Others

1.00

 

1.00

 

WHO stage

 1 or 2

1.00

< 0.001

1.00

0.003

 3 or 4

0.52 (0.41–0.74)

 

0.63 (0.46–0.85)

 

CD4 cell count < 200, cells/mm3

 < 200

1.43 (1.16–1.76)

< 0.001

1.71 (1.36–2.16)

< 0.001

 200 +

1.00

 

1.00

 
  1. 1 Relative riskPrevalence Ratio (PRR), 95% confidence interval (CI) and p-values were calculated using log binomial regression
  2. 2 Multivariate models included all predictors significant at p value < 0.20