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Table 1 Relevant laboratory tests from baseline to discharge

From: Cytomegalovirus and disseminated histoplasmosis-related hemophagocytic lymphohistiocytosis syndrome in an HIV-patient late presenter with IRIS: a case report

Test (units) (reference values)

Day 0

Day 6

Day 15

Day 23

Day 29

Day 62

Hemoglobin (g/dL) (12.2–18.1)

6.0d

8.04

6.3

7.9

12.2

11.01

Platelets (× 103/μL) (142–424)

21.53d

6.99

39.75

30.98

350.10

112.40

White blood cells (× 103/μL) (4.6–10.2)

2.15d

2.13

10.68

3.00

4.54

2.09

Neutrophils (× 103/μL) (37–80%)

1.72

1.97

10.03

2.75

4.29

1.58

Creatinine (mg/dL) (0.5–1.2)

1.38

1.4

0.92

0.36

0.87

0.41

Urea (mg/dL) (15–39)

92.9

90

103.9

44

25.8

26

Glucose (mg/dL) (60–125)

125a

159b

116b

130b

101

86

Sodium (mEq/L) (135–145)

126

128

128

134

138

137

Potassium (mEq/L) (3.5–5.1)

5.6

5.4

5.0

3.73

3.6

3.47

ALT (IU/L) (10–40)

20

33

25

19

13

9

AST (IU/L) (10–50)

173

83

32

18

18

9

CK (U/L) (38–174)

40

Albumin (g/dL) (3.5–5.0)

1.3

1.97

2.03

2.00

2.14

3.82

Total Bilirubin (mg/dL) (0–1)

1

0.5

0.2

0.25

0.6

0.31

LDH (IU/L) (91–190)

1059

208

127

100

116

100

PT (s) (9.5–13)

15.1

14.3

16

14

15.4

11.5

PTT (s) (25.5–35.5)

43.2

42.2

39.2

49

39.1

34.7

INR [1]

1.36

1.29

1.54

1.35

1.39

1.10

Triglycerides (mg/dL) (35–160)

284d

84

Fibrinogen (mg/dL) (200–480)

233d

553

683

864

633

613

Ferritinc (ng/mL) (20–250)

> 5000d

4061.7

D-Dimer (ng/mL) (< 500)

4557

1929

CRP (mg/L) (< 10)

56.9

12.7

  1. PT, Prothrombin time; TPT, partial thromboplastin time; INR, international normalized ratio; ALT, alanine aminotransferase; AST, aspartate aminotransferase; LDH, lactate dehydrogenase; CRP, C-reactive protein; CK, creatine kinase
  2. aNon-fasting glucose; b patient under corticotherapy; c The ferritin lab test provided in our hospital has an upper max limit of 5000 ng/mL; d Parameter that fulfilled HLS diagnostic criteria