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Table 1 Comparison of participants with and without HIVDR testing

From: Pretreatment resistance mutations and treatment outcomes in adults living with HIV-1: a cohort study in urban Malawi

 

Participants

P

No HIVDR testing

HIVDR testing

 n

1235

197

 

 Sex (%)

  Female

692 (56.0)

122 (61.9)

0.140a

  Male

543 (44.0)

75 (38.1)

 

  Age [mean (SD)]

36.20 (9.31)

35.09 (9.11)

0.118b

  BMI [mean (SD)]

24.28 (4.91)

23.93 (4.63)

0.348b

 WHO stage (%)

  1

531 (43.0)

128 (65.0)

< 0.001a

  2

183 (14.8)

38 (19.3)

 

  3

429 (34.7)

19 (9.6)

 

  4

92 (7.4)

12 (6.1)

 

 CD4 count (median [IQR])

269.5 [125; 420]

247.5 [89; 420]

0.230c

  Viral load (median [IQR])

33 000 [6 696; 140 844]

112 599 [21 318; 454 638]

< 0.001c

 Outcome (%)

  Alive on ART

715 (57.9)

119 (60.4)

0.020a

  Defaulted

267 (21.6)

32 (16.2)

 

  Transferred out

118 (9.6)

21 (10.7)

 

  Changed ART regimen

62 (5.0)

3 (1.5)

 

  Died

41 (3.3)

14 (7.1)

 

  Withdrawn

27 (2.2)

7 (3.6)

 

  Stopped ART

5 (0.4)

1 (0.5)

 
  1. CD4 count: number of CD-4 positive T-cells per µl; viral load: number of copies of HIV-1 RNA per ml of Serum
  2. n number of participants, SD standard deviation, IQR interquartile range, HIVDR HIV-1 drug resistance mutation, BMI body mass index, kg/m2, WHO stage World Health Organization stage of clinical HIV illness
  3. aChi2 test; bStudent’s t test; cKruskal Wallis test