|
HIV+
|
Controls
|
p
|
---|
N
|
38
|
11 *
|
–
|
Gender (M/F)
|
14/24 (37%/63%)
|
4/7 (36%/64%)
|
0.97 (χ2)
|
Age at Griffiths (months)
|
60.9 (1.3)
|
63.3 (4.8)
|
0.12
|
Range
|
58.0–64.5
|
59.5–71.0
|
–
|
Age at scan (months)
|
64.7 (3.5)
|
67.7 (5.5)
|
0.11
|
Range
|
58.8–74.4
|
61.2–74.4
|
–
|
Time between Griffiths and scan (days)
|
119.2 (104.3)
|
128.3 (131.8)
|
0.81
|
Range
|
0–386
|
21–392
|
–
|
Age starting ART (weeks)
|
18 (16.8)
|
NA
|
–
|
Range
|
7.0–75.7
| |
–
|
Cumulative Time on ART (weeks)
|
234 (50.8)
|
NA
|
–
|
CD4
| |
NA
|
–
|
Baseline
|
1965.4 (939.8)
|
–
|
–
|
Nadir
|
703.2 (391.6)
|
–
|
–
|
At scan
|
1132.7 (480.7)
|
–
|
–
|
CD4%
| |
NA
|
–
|
Baseline
|
34.5 (10)
|
–
|
–
|
Nadir
|
20.4 (6.5)
|
–
|
–
|
At scan
|
35.2 (8.2)
|
–
|
–
|
CD8
| |
NA
|
–
|
Baseline
|
1693.3 (899.3)
|
–
|
–
|
Nadir
|
575.4 (329.1)
|
–
|
–
|
At scan
|
1025.7 (536.9)
|
–
|
–
|
Griffiths Q scores
|
Locomotor
|
96.1 (16.2)
|
93.0 (11.9)
|
0.57
|
Personal social
|
90.8 (9.4)
|
96.4 (9.0)
|
0.08
|
Language
|
75.4 (10.7)
|
77.7 (10.7)
|
0.53
|
Eye hand coordination
|
85.4 (9.0)
|
84.3 (12.2)
|
0.74
|
Performance
|
75.4 (10.5)
|
78.0 (19.5)
|
0.57
|
Practical reasoning
|
76.7 (8.6)
|
75.2 (11.4)
|
0.65
|
General
|
83.5 (6.5)
|
84.1 (8.3)
|
0.81
|
Beery-Buktenica
|
Visual motor integration
|
91 (9.1)
|
87.4 (7.2)
|
0.23
|
Visual perception
|
76.7 (14.7)
|
83.1 (13.7)
|
0.22
|
Motor co-ordination
|
94.8 (8.3)
|
93.2 (10.4)
|
0.59
|
- Values: mean (standard deviation) unless otherwise stated
- * 9 HIV exposed and uninfected, 2 unexposed