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Table 2 Demographics and neurodevelopmental scores of the HIV+ group and controls

From: Diffusion tensor imaging point to ongoing functional impairment in HIV-infected children at age 5, undetectable using standard neurodevelopmental assessments

 

HIV+

Controls

p

N

38

11 *

–

Gender (M/F)

14/24 (37%/63%)

4/7 (36%/64%)

0.97 (χ2)

Age at Griffiths (months)

60.9 (1.3)

63.3 (4.8)

0.12

 Range

58.0–64.5

59.5–71.0

–

Age at scan (months)

64.7 (3.5)

67.7 (5.5)

0.11

 Range

58.8–74.4

61.2–74.4

–

Time between Griffiths and scan (days)

119.2 (104.3)

128.3 (131.8)

0.81

 Range

0–386

21–392

–

Age starting ART (weeks)

18 (16.8)

NA

–

 Range

7.0–75.7

 

–

Cumulative Time on ART (weeks)

234 (50.8)

NA

–

CD4

 

NA

–

 Baseline

1965.4 (939.8)

–

–

 Nadir

703.2 (391.6)

–

–

 At scan

1132.7 (480.7)

–

–

CD4%

 

NA

–

 Baseline

34.5 (10)

–

–

 Nadir

20.4 (6.5)

–

–

 At scan

35.2 (8.2)

–

–

CD8

 

NA

–

 Baseline

1693.3 (899.3)

–

–

 Nadir

575.4 (329.1)

–

–

 At scan

1025.7 (536.9)

–

–

Griffiths Q scores

 Locomotor

96.1 (16.2)

93.0 (11.9)

0.57

 Personal social

90.8 (9.4)

96.4 (9.0)

0.08

 Language

75.4 (10.7)

77.7 (10.7)

0.53

 Eye hand coordination

85.4 (9.0)

84.3 (12.2)

0.74

 Performance

75.4 (10.5)

78.0 (19.5)

0.57

 Practical reasoning

76.7 (8.6)

75.2 (11.4)

0.65

 General

83.5 (6.5)

84.1 (8.3)

0.81

Beery-Buktenica

 Visual motor integration

91 (9.1)

87.4 (7.2)

0.23

 Visual perception

76.7 (14.7)

83.1 (13.7)

0.22

 Motor co-ordination

94.8 (8.3)

93.2 (10.4)

0.59

  1. Values: mean (standard deviation) unless otherwise stated
  2. * 9 HIV exposed and uninfected, 2 unexposed