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Table 2 Demographics and neurodevelopmental scores of the HIV+ group and controls

From: Diffusion tensor imaging point to ongoing functional impairment in HIV-infected children at age 5, undetectable using standard neurodevelopmental assessments

  HIV+ Controls p
N 38 11 *
Gender (M/F) 14/24 (37%/63%) 4/7 (36%/64%) 0.97 (χ2)
Age at Griffiths (months) 60.9 (1.3) 63.3 (4.8) 0.12
 Range 58.0–64.5 59.5–71.0
Age at scan (months) 64.7 (3.5) 67.7 (5.5) 0.11
 Range 58.8–74.4 61.2–74.4
Time between Griffiths and scan (days) 119.2 (104.3) 128.3 (131.8) 0.81
 Range 0–386 21–392
Age starting ART (weeks) 18 (16.8) NA
 Range 7.0–75.7  
Cumulative Time on ART (weeks) 234 (50.8) NA
CD4   NA
 Baseline 1965.4 (939.8)
 Nadir 703.2 (391.6)
 At scan 1132.7 (480.7)
CD4%   NA
 Baseline 34.5 (10)
 Nadir 20.4 (6.5)
 At scan 35.2 (8.2)
CD8   NA
 Baseline 1693.3 (899.3)
 Nadir 575.4 (329.1)
 At scan 1025.7 (536.9)
Griffiths Q scores
 Locomotor 96.1 (16.2) 93.0 (11.9) 0.57
 Personal social 90.8 (9.4) 96.4 (9.0) 0.08
 Language 75.4 (10.7) 77.7 (10.7) 0.53
 Eye hand coordination 85.4 (9.0) 84.3 (12.2) 0.74
 Performance 75.4 (10.5) 78.0 (19.5) 0.57
 Practical reasoning 76.7 (8.6) 75.2 (11.4) 0.65
 General 83.5 (6.5) 84.1 (8.3) 0.81
Beery-Buktenica
 Visual motor integration 91 (9.1) 87.4 (7.2) 0.23
 Visual perception 76.7 (14.7) 83.1 (13.7) 0.22
 Motor co-ordination 94.8 (8.3) 93.2 (10.4) 0.59
  1. Values: mean (standard deviation) unless otherwise stated
  2. * 9 HIV exposed and uninfected, 2 unexposed