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Table 1 Quality indicators definition and their respective site performance levels [11]

From: Programme quality indicators of HIV drug resistance among adolescents in urban versus rural settings of the centre region of Cameroon

PQI title

Definition

Numerator

Denominator

Performance

PQI-1

On-time ARV drug pick-up

Percentage of adolescents that pick-up ART no more than 2 days late at the first pick-up after the baseline pick-up.

Number of adolescents picking-up their ART “on time” at the first drug pick-up after baseline pick-up date

Number of adolescents who picked-up ARV drugs on or after the designated PQI sample start date

The desirable performance (green): > 90%, Fair performance (amber): 80–90%, Poor performance (red): < 80%

PQI-2

Retention in care

Percentage of adolescents known to be alive and on ART 12 months after enrolment

Number of adolescents who are still alive and on ART 12 months after enrolment

Total number of adolescents (excluding transfers out) who were expected to achieve 12-month outcomes

Desirable performance (green): > 85%

Fair performance (amber): 75–85%

Poor performance (red): < 75%

PQI-3 Antiretroviral drug stock outs

Percentage of antiretroviral drug stock-outs during a 12-month period

Number of months in the year in which there were ARV drug stock outages for any ARVs in any of the standard ART regimens supplied by the site or the pharmacy at which the site’s patients pick up ARV drugs

12 months

The desirable performance: Zero (0%)

PQI-4 Dispensing Practices

Percentage of adult patients picking up mono or dual ARV therapy

Number of adolescents who pick up from the pharmacy, a regimen consisting of one or two ARVs

Number of adolescents picking up ART on or after the designated EWI sample start date

The desirable performance (green): 0%; Poor performance (red): > 0%

PQI-5

Viral load coverage

Number of patients who by national policy should have received a 12-month viral load test, by clinic

Number of adolescents who have a viral load performed at 12 months after enrolment

Total number of adolescents on ART on site (excluding transfers out) 12 months after enrolment

Desirable performance (green): ≥ 70%

Poor performance (red): < 70%

PQI-6

Viral load suppression

Percentage of adolescents receiving ART of ART whose viral load is < 1000 copies/ml 12 months after enrolment

Number of adolescents receiving ART 12 months after study enrolment and whose viral load is < 1000 copies/ml

Number of adolescents who have a viral load performed at 12 months after enrolment

Desirable performance (green): > 90%, Fair performance (amber): 70–90%, Poor performance (red): < 70%

PQI-7

Adequate switch to second-line antiretroviral therapy regimens

Percentage of adolescents on ART on site with a change of therapy from first line ART to second line ART based on viral load result

Number of adolescents on second line ART on site after 12 months

Number of adolescents on ART on site after 12 months

The desirable performance: 100% of people switch to second-line antiretroviral therapy guided by a viral load result

  1. ARV: antiretroviral; ART: Antiretroviral therapy; PQI: programme quality indicator