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Table 2 Logistic regression for the associations between normalisation of the CD4+:CD8+ ratio and IFNL genotypes in PLWH on ART with viral suppression

From: Interferon lambda rs368234815 ΔG/ΔG is associated with higher CD4+:CD8+ T-cell ratio in treated HIV-1 infection

SNP

Normalised (n = 31)

Not Normalised (n = 80)

Unadjusted OR (95% CI)

Adjusted OR (95% CI)a

rs12979860

 C/C

9

30

1 (referent)

1 (referent)

 C/T

16

41

1.30 (0.51; 3.34)

1.31 (0.48; 3.55)

 T/T

6

9

2.22 (0.62; 7.94)

2.28 (0.60; 8.69)

rs368234815

 T/T

10

38

1 (referent)

1 (referent)

 T/ΔG

12

31

1.47 (0.56; 3.89)

1.69 (0.62; 4.60)

 ΔG/ΔG

9

11

3.11 (1.01; 9.56)

2.80 (0.82; 9.54)

  1. aAdjusted for age, gender, treatment duration and duration of HIV-infection
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AIDS Research and Therapy

ISSN: 1742-6405

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