Pre-switchd | Post-switchd | p value | |
---|---|---|---|
CD4+ T-cells (cells/μl) | 624 (512–783) | 662 (530–833) | < 0.001 |
CD8+ T-cells (cells/μl) | 574 (449–787) | 618 (482–797) | 0.155 |
CD4/CD8 | 1.09 (0.85–1.41) | 1.12 (0.87–1.43) | 0.026 |
NPZ-4 | 0.70 (0.31–1.10) | 0.88 (0.37–1.19) | < 0.001 |
Color Trails 1 z-score | 1.15 (0.59–1.56) | 1.30 (0.64–1.74) | 0.001 |
Color Trails 2 z-score | 0.61 (0.14–1.11) | 0.86 (0.40–1.22) | < 0.001 |
Grooved pegboard test z-score | 0.54 (− 0.20–1.05) | 0.64 (− 0.09–1.10) | 0.149 |
Trail making A z-score | 0.75 (0.14–1.15) | 0.80 (0.07–1.33) | 0.037 |
PHQ-9 score | 5 (1–7) | 5 (2–8) | 0.009 |
PHQ-9 ≥ 10, n (%) | 24 (10) | 40 (16) | 0.006 |
PHQ-9 ≥ 15, n (%) | 8 (3) | 8 (3) | 1.000 |
PHQ-9 somatic sub-scorea | 2 (0–3) | 2 (1–3) | 0.007 |
PHQ-9 cognitive/affective sub-scoreb | 2 (0–4) | 2 (0–5) | 0.064 |
Major depression by 2Q-depression screening, n (%) | 2 (1) | 3 (1) | 1.000 |
Distress thermometer score | 2 (1–5) | 2 (1–4) | 0.898 |
Viral suppression, n (%)c | 244 (96) | 250 (98) | 0.070 |