Parameter | Sub-parameter | Immediate treatment | Deferred treatment | p-value (if applicable) |
---|---|---|---|---|
Eventa (frequency row %) | No event | 22 (70.97) | 21 (70.00) | 0.934 (computed by Chi-square) |
Event | 9 (29.03) | 9 (30.00) | ||
Hospitalization (days) | Mean (absolute) | 33.2 ± 19.1 | 34.57 ± 23.6 | 0.6125 (computed by t-test) |
Range (absolute) | 141 | 205 | ||
Incidence of IRIS (%) | Yes | 11 (35.48) | 10 (33.33) | 0.8597 (computed by Chi-square) |
No | 20 (64.52) | 20 (66.67) | ||
Virological outcome week 24 (more than 400 or 50 copies/mL) | Number of patients with HIV RNA > 50 cop/mL | 12 | 12 | 0.6740 (computed by Chi-square) |
With HIV RNA > 400 cop/mL | 1 | 1 | 1.0 (computed by Fisher’s Exact test) | |
Immunological outcome (week 24): CD4 cells | Absolute mean | 126 (± 42.1) | 137 (± 44.0) | 0.6421 (computed by t-test) |
Delta mean | 99 | 95 | ||
Quality of life | SF 36 body score (sum of scores) | 5706 | 5772 | 0.7978 |
SF 36 psychological score (sum of scores) | 5622 | 5106 | 0.7978 (each computed by Wilcoxon test) | |
AE-severity by treatment (%) | Grade 1 event | 61 (22.26) | 73 (26.64) | 0.4682 (computed by Fisher’s Exact test) |
Grade 2 event | 53 (19.34) | 55 (20.07) | ||
Grade 3 event | 6 (2.19) | 11 (4.01) | ||
Grade 4 event | 3 (1.09) | 6 (2.19) | ||
Unknown severity | 1 (0.38) | 5 (1.82) | ||
Total | 124 (45.26) | 150 (54.74) | ||
PCP | 4 events | 6 events | 0.6372 (number of events between TE/PCP; computed by Chi-square) | |
TE | 5 events | 3 events |