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Table 1 Characteristics at ART start by gender patients initiated on standard first line antiretroviral therapy at the Infectious Diseases Institute Kampala, Uganda

From: Reasons for first line ART modification over the years during the ART scale up in Uganda

Characteristics

Overall

N = 14,261

(100%)

Female

N = 9114 (63.9%)

Male

N = 5147 (36.1%)

P value

Age in completed years, median (IQR)

36 (30–42)

34 (29–40)

38 (33–44)

< 0.001

WHO stage 3 and 4, n (%)

7749 (60.8)

4533 (55.8)

3216 (69.7%)

< 0.001

BMI, kg/m2, median, (IQR) n (%)a

21.9 (19.6–24.8)

22.7 (20.1–25.8)

20.8 (19–22.9)

< 0.001

 Underweight (< 18.5)

1975 (14.7)

1037 (12.1)

938 (19.4)

< 0.001

 Normal (18.5–25)

8231 (64.4)

4926 (57.5)

3305 (68.4)

 

 Overweight (> 25)

3196 (23.9)

2604 (30.4)

592 (12.24)

CD4 count, cells/µL, median (IQR)b

< 0.001

< 0.001

 n (%)

188 (65–353)

210 (80–380)

153 (47–300)

 < 200 cells/µL

7274 (52.2)

4317 (48.2)

2957 (59.3)

 200–350 cells/µL

3139 (22.5)

2094 (23.4)

1045 (21)

 

 > 350 cells/µL

3519 (25.3)

2537 (28.4)

982 (19.7)

 

Period of ART start, n (%)

0.682

 2005–2008

6879 (48.2)

4408 (48.4)

2471 (48.0)

 2009–2017

7382 (51.8)

4706 (51.6)

2676 (52.0)

ART regimen n, (%)

0.007

 Stavudine

3932 (27.5)

2565 (28.2)

1367 (25.6)

 Zidovudine

6555 (46.0)

4213 (46.2)

2342 (45.5)

 Tenofovir

3774 (26.5)

2336 (25.6)

1438 (27.9)

  1. IQR interquartile range, BMI body mass index, ART antiretroviral treatment
  2. aMissing for 859 patients
  3. bMissing for 144 patients