Table 3 Factors associated with virologic failure in children on antiretroviral therapy
From: Long-term virological outcome in children receiving first-line antiretroviral therapy
Variable | Univariate analysis | Multivariate analysis | ||
|---|---|---|---|---|
Odds ratio (95% CI) | p value | Odds ratio (95% CI) | p value | |
Age (years) | ||||
 ≤ 5 |  | 0.63 |  | 0.97 |
 > 5 | 1.19 (0.50–1.74) |  | 1.02 (0.45–2.26) |  |
Gender | ||||
 Girls |  | 0.81 |  | 0.62 |
 Boys | 1.07 (0.57–2.01) |  | 0.85 (0.45–1.59) |  |
ART regimen | ||||
 Nevirapine |  | 0.06 |  | 0.48 |
 Efavirenz | 2.15 (0.88–5.38) |  | 1.77 (0.36–8.67) |  |
Primary caregiver | ||||
 Yes |  | 0.06 |  | 0.26 |
 No | 0.42 (0.15–1.13) |  | 0.58 (0.21–1.52) |  |
Staying in a residential institution | ||||
 Yes |  | 0.71 |  | 0.46 |
 No | 1.15 (0.49–2.68) |  | 1.36 (0.58–3.19) |  |
TB status | ||||
 No |  | 0.09 |  | 0.95 |
 Yes | 0.50 (0.20–1.21) |  | 0.95 (0.19–4.73) |  |
CD4 at baseline | ||||
 < 350 cells/mm3 |  | 0.16 |  | 0.18 |
 > 350 | 1.53 (0.80–2.91) |  | 1.56 (0.80–3.00) |  |
Viral load at baseline (copies/ml) | ||||
 ≤ 400 |  | 0.51 |  | 0.24 |
 > 400 | 2.48 (0.0–92.47) |  | 3.49 (0.42–28.8) |  |
WAZ score | ||||
 > − 2.00 |  | 0.23 |  | 0.25 |
 ≤ − 2.00 | 0.69 (0.36–1.38) |  | 0.62 (0.28–1.39) |  |
HAZ score | ||||
 > − 2.00 |  | 0.51 |  | 0.78 |
 ≤ − 2.00 | 0.82 (0.43–1.55) |  | 0.89 (0.42–1.91) |  |