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Table 2 Clinical and immunological outcome of children on ART during 24 months of follow-up

From: Long-term virological outcome in children receiving first-line antiretroviral therapy

Laboratory parameters

Baseline (n = 393)

6 months (n = 340)

12 months (n = 323)

24 months (n = 234)

Mean (SD) hemoglobin (g/dl)

10.60 (1.64)

11.33 (1.46)

11.63 (1.44)

11.8 (1.3)

Mean (SD) CD4%

16.24 (7.93)

26.67 (9.54)

29.31 (9.47)

35.38 (36)$

Anthropometry n (%)

n = 393

n = 340

n = 323

n = 218

 WAZ score < − 2

225 (57)

119 (35)

71 (22)*

16 (7)$

 HAZ score < − 2

205 (52)

112 (33)

69 (21)*

17 (8)$

 WHZ score < − 2

68 (17)

35 (10)

27 (8)*

23 (11)$

 CD4%

n (%) = 345

n (%) = 284

n (%) = 243

n (%) = 135

  < 25%

278 (81)

117 (41)

75 (31)*

33 (24)$

  > 25%

67 (19)

170 (60)

168 (69)*

102 (76)$

CD4 cell count (> 5 years of age)

n (%) = 304

n = 273

n = 261

n = 193

 > 350 cells/mm3

152 (50)

245 (90)

238 (91)*

176 (91)$

 < 350 cells/mm3

152 (50)

28 (10)

28 (11)*

17 (9)$

Viral load (copies/ml)

n (%) = 389

n (%) = 348

n (%) = 328

n (%) = 218

 < 400

11 (3)

273 (78)

221 (67)*

150 (69)$

 400–1000

17 (4)

10 (3)

13 (4)

5 (2)

 > 1000

361 (93)

70 (20)

94 (29)*

63 (29)$

  1. WAZ weight for age, HAZ height for age, WHZ weight for height
  2. * p < 0.05 between baseline and 12 months
  3. $ p < 0.05 between baseline and 24 months by Mcnemar’s test