Factors associated with viral non-suppression among adolescents living with HIV in Cambodia: a cross-sectional study

Table 5 Factors associated with viral non-suppression among adolescents living with HIV (n = 328)

Variables in the model	Viral non-suppression^a
Variables in the model	OR (95% CI)	p-value	AOR (95% CI)	p-value^†
Age group
15	Reference		Reference
16	0.76 (0.42–1.38)	0.37	0.80 (0.40–1.57)	0.51
17	0.47 (0.24–0.92)	0.03	0.46 (0.21–0.98)	0.04
Duration on ART^† (years)
≤ 9	Reference		Reference
> 9	0.26 (0.15–0.45)	< 0.001	0.35 (0.19–0.64)	0.001
Most recent CD4 count^†
≤ 672	Reference		Reference
> 672	0.45 (0.26–0.77)	0.003	0.47 (0.26–0.86)	0.02
First viral load^†
≤ 628 RNA copies/mL	Reference		Reference
> 628 RNA copies/mL	2.04 (1.04–2.50)	0.02	1.92 (1.02–4.42)	0.04
Main daily care giver
Parent	Reference		Reference
Grand parent	0.56 (0.06–5.08)	0.60	0.72 (0.06–6.10)	0.80
Sibling	0.32 (0.09–0.11)	0.07	0.30 (0.07–1.18)	0.08
Relatives	0.28 (0.14–0.55)	< 0.001	0.37 (0.17–0.80)	0.01
Orphanage/NGO staff	0.74 (0.19–2.84)	0.66	0.49 (0.10–2.32)	0.37
Receiving HIV care and treatment from:
Pediatric ART clinic	Reference		Reference
Adult ART clinic	3.26 (1.88–5.64)	< 0.001	2.95 (1.56–5.59)	0.001
There is a cure for AIDS
True	Reference		Reference
False	0.32 (0.18–0.57)	< 0.001	0.40 (0.21–0.75)	0.005
Receiving HIV care and treatment from:
Pediatric ART clinic	Reference		Reference
Adult ART clinic	3.26 (1.88–5.64)	< 0.001	2.95 (1.56–5.59)	0.001

Age, gender, and all variables associated with viral non-suppression at a level of p < 0.05 were simultaneously included in a multivariate logistic regression model
AOR adjusted odds ratio, ART antiretroviral therapy, CI confidence interval
^aViral load count of < 1000 RNA copies/mL
^†Median value was used as a cutoff to categorize the variables

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