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Table 1 Summary table for associated mutations for Q151M (n = 180 patients)

From: Risk factors and outcomes for the Q151M and T69 insertion HIV-1 resistance mutations in historic UK data

 

n (%)

Q151M isolated major RT mutation

5 (3)

Q151M accessory mutationsa

 0

38 (25)

 1

50 (32)

 2

14 (9)

 3

33 (21)

 4

20 (13)

NRTI major mutations other than Q151M

 0

20 (11)

 1

44 (24)

 2

45 (25)

 3

32 (18)

 4

24 (13)

 5

14 (8)

 6

1 (1)

TAMs presentb

 0

82 (46)

 1

40 (22)

 2

18 (10)

 3

23 (13)

 4

15 (8)

 5

2 (1)

NNRTI major mutations

 0

35 (19)

 1

43 (24)

 2

64 (36)

 3

24 (13)

 4

11 (6)

 5

3 (2)

PI major mutationsc

 0

108 (60)

 1

33 (18)

 2

14 (8)

 3

10 (6)

 4

9 (5)

 5

1 (1)

 6

4 (2)

Number of classes with resistanced

 1

17 (9)

 2

110 (61)

 3

53 (29)

  1. aIncluding A62V, V75I, F77L and F116Y, data available for 155 patients
  2. bM41L, D67N, K70R, L210W, T215Y/F and K219Q/E
  3. cPI PCR failed in one case.
  4. dOf NRTI, NNRTI and PI. A full list of mutations and further information regarding associated K65R mutations are provided in Additional file 1