Fig. 1

Prevalence of (a) the Q151M mutation and (b) the T69i mutation per patient by calendar year of sequencing (patients can be included in multiple calendar years, but are only counted once per year), according to whether the patient was ART experienced (black circle) or naïve (orange circle) at the time of blood sample. The denominator in each year is the total number of patients with at least one reverse transcriptase sequence recorded in that year. Binomial 95% CIs are shown