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Table 4 WHO multivariate model (variables were WHO danger signs) and augmented multivariate model (variables were the WHO danger signs, and the following: CD4 count, body mass index, being on ART, hypotension, and confusion) for predicting the secondary outcome (any one of: hospital admission for > 7 days, death in hospital, transfer to a tertiary level hospital, or transfer to a tuberculosis hospital)

From: Prognostic indicators in the World Health Organization’s algorithm for seriously ill HIV-infected inpatients with suspected tuberculosis

Variable

WHO multivariate model

Augmented multivariate model

Category

aORa

95% confidence interval

Wald’s p value

aOR

95% confidence interval

Wald’s p value

Respiratory rate > 30

 No

Referent group

 

Referent group

 

 Yes

1.19

0.79 to 1.79

0.408

1.21

0.79–1.85

0.376

Heart rate > 120

 No

Referent group

 

Referent group

 

 Yes

0.96

0.60 to 1.55

0.883

0.93

0.57–1.52

0.722

Temperature > 39 °C

 No

Referent group

 

Referent group

 

 Yes

1.01

0.60 to 1.68

0.980

0.97

0.57–1.64

0.899

Unable to walk

 No

Referent group

 

Referent group

 

 Yes

4.48

3.05 to 6.57

< 0.001

3.96

2.66–5.90

< 0.001

CD4 cells/µLb

   

0.85

0.73–0.98

0.025

BMI (kg/m2)c

   

0.97

0.93–1.00

0.073

On ART at admission

    

 No

  

Referent group

 

 Yes

   

1.28

0.84–1.96

0.249

Hypotensived

      

 No

  

Referent group

 

 Yes

   

0.95

0.60–1.52

0.838

Confused

      

 No

  

Referent group

 

 Yes

   

1.48

0.87–2.53

0.146

  1. Imputation set used due to missing CD4 and BMI data
  2. aAdjusted odds ratio
  3. bIncrease in increments of 100 cells/µl
  4. cIncrease per 1 kg/m2
  5. dSystolic blood pressure < 90 mmHg or diastolic blood pressure ≤ 60 mmHg