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Table 3 WHO multivariate model (variables were WHO danger signs) and augmented multivariate model (variables were the WHO danger signs, and the following: CD4 count, body mass index, being on ART, hypotension, and confusion) for predicting death at 56 days post-discharge. Imputation set used due to missing CD4 and BMI data

From: Prognostic indicators in the World Health Organization’s algorithm for seriously ill HIV-infected inpatients with suspected tuberculosis

Variable

WHO multivariate model

Augmented multivariate model

Category

aORa

95% confidence interval

Wald’s p value

aOR

95% confidence interval

Wald’s p value

Respiratory rate > 30

 No

Referent group

 

Referent group

 

 Yes

1.25

0.68 to 2.29

0.469

1.05

0.55–2.02

0.879

Heart rate > 120

 No

Referent group

 

Referent group

 

 Yes

0.68

0.36 to 1.29

0.240

0.59

0.29–1.19

0.138

Temperature > 39 °C

 No

Referent group

 

Referent group

 

 Yes

0.66

0.28 to 1.52

0.329

0.67

0.28–1.59

0.364

Unable to walk

 No

Referent group

 

Referent group

 

 Yes

2.94

1.58 to 5.47

0.001

2.06

1.06–3.99

0.032

CD4 cells/µLb

   

0.62

0.45–0.86

0.004

BMI (kg/m2)c

   

1.02

0.96–1.08

0.535

On ART at admission

    

 No

  

Referent group

 

 Yes

   

2.54

1.37–4.72

0.003

Hypotensived

 No

  

Referent group

 

 Yes

   

1.10

0.55–2.23

0.782

Confused

 No

  

Referent group

 

 Yes

   

1.48

0.71–3.06

0.295

  1. aAdjusted odds ratio
  2. bIncrease in increments of 100 cells/µL
  3. cIncrease per 1 kg/m2
  4. dSystolic blood pressure < 90 mmHg or diastolic blood pressure ≤ 60 mmHg