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Table 3 Cox regression model for IRIS development

From: Clinical characteristics, predictors of immune reconstitution inflammatory syndrome and long-term prognosis in patients with Kaposi sarcoma

Characteristics

IRIS-KS (n = 35)

Non-IRIS-KS (n = 54)

Unadjusted HR (95% CI)

p value

Adjusted HR (95% CI)

p value

IRIS

 HIV-RNA at follow-upa

  <100 copies/mm3

25 (81)

48 (96)

1.00

   

  >100 copies/mm3

6 (19)

2 (4)

5.76 (0.92–61)

0.04

2.26 (0.58–8.89)

0.239

 Pulmonary involvement

  No

14 (40)

45 (83)

1.00

   

  Yes

21 (60)

9 (17)

7.5 (2.53–22.79)

<0.0001

3.20 (1.12-9.12)

0.02

 Platelets at follow-upb

  >100,000/mm3

20 (65)

48 (96)

1.00

   

  <100,000/mm3

11 (35)

2 (4)

13.2 (2.46–128.61)

0.003

2.79 (0.92–8.43)

0.06

  1. aDetectable viral load >1000 copies/mm3 at 12-week follow up. Viral load was documented in 81 patients
  2. bPlatelets <100,000/mm3 at 12-weeks follow-up. 81 patients had platelets count at follow-up