Table 1 Measurements and data collected in the CoLTART cohort
Phase | Data collected at enrolment |
|---|---|
Baseline July 2013 | Demographic data and self-reported social economic status Medical, dietary and socio-economic and behavioural risk factors Biophysical measurements: weight, height, blood pressure, pulse rate; waist, hip and mid-upper arm circumferences Clinical examination Antiretroviral therapy and cotrimoxazole/dapsone adherence Laboratory measurements data Biochemistry (i) Fasting blood lipid profiles: total cholesterol, triglycerides, low density lipoproteins, high density lipoproteins (ii) Fasting blood glucose (iii) Renal function tests: urine strip testing, phosphates and creatinine Serum phosphates, creatinine and urea (vi) Liver function tests: alanine transaminase, aspartate transaminase, alkaline phosphatase and bilirubin Haematology and immunology (i) Full blood counts (ii) CD3, CD4 and CD8 cell counts Virology (i) HIV viral loads (ii) HIV drug resistance testing—when indicated Serology (for future testing) Serum for Hepatitis B virus serology and plasma aliquots stored at −80 °C |
6 monthly Follow-up January 2014 | Data collected at follow up Biophysical measurements Medical, dietary and socio-economic and behavioural risk factors Clinical examination Antiretroviral therapy and cotrimoxazole/dapsone adherence Laboratory measurements Fasting blood glucose and lipid profiles Renal and liver function tests Full blood counts and immunology—CD3, CD4 and CD8 HIV viral loads HIV drug resistance testing—when indicated Whole blood for genomics studies stored at −80 °C (once) |