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Table 1 Hospitalized patient clinical and demographic characteristics by IRIS and study period

From: Hospital days attributable to immune reconstitution inflammatory syndrome in persons living with HIV before and after the 2012 DHHS HIV guidelines

 

Total study duration n (%)

Subjects with Time Period 1 non IRIS-attributable hospitalization n (%)

Subjects with Time Period 1 IRIS-attributable hospitalization n (%)

p value

Subjects with Time Period 2 non IRIS-attributable hospitalization n (%)

Subjects with Time Period 2 IRIS-attributable hospitalization n (%)

p value

Total subjects

278

151

9

 

112

6

 

Mean age

47.5

47.7

42.8

0.17

47.7

47.3

0.94

Sexa

   

0.73

  

0.66

 Male

192 (69)

105 (70)

7 (78)

 

75 (67)

5 (83)

 

 Female

86 (31)

46 (30)

2 (22)

 

37 (33)

1 (17)

 

Race/ethnicity

   

0.08

  

0.008

 White

121 (44)

61 (40)

2 (22)

 

58 (52)

0 (0)

 

 Black

147 (53)

84 (56)

5 (56)

 

53 (47)

5 (83)

 

 Hispanic

5 (2)

4 (3)

1 (11)

 

0 (0)

0 (0)

 

 Other/unknown

5 (2)

2 (1)

1(11)

 

1 (1)

1 (17)

 

CD4 countb

   

0.004

  

0.18

 <200

112 (40)

59 (39)

8 (89)

 

40 (36)

5 (83)

 

 200–500

86 (31)

47 (31)

1 (11)

 

37 (33)

1 (17)

 

 >500

69 (25)

39 (26)

0 (0)

 

30 (27)

0 (0)

 

HIV viral loadc

   

0.54

  

0.04

 <200

154 (55)

89 (59)

4 (44)

 

60 (54)

1 (17)

 

 200–1000

10 (4)

7 (5)

0 (0)

 

2 (2)

1 (17)

 

 >1000

103 (37)

49 (32)

5 (56)

 

45 (40)

4 (66)

 

Hepatitis B co-infectiond

   

0.47

  

0.21

 Chronic infection

59 (21)

15 (10)

2 (22)

 

15 (13)

1 (17)

 

 Exposure and clearance

33 (12)

35 (23)

1 (11)

 

20 (18)

3 (50)

 

 No exposure or infection

162 (58)

88 (58)

5 (56)

 

67 (60)

2 (33)

 

Hepatitis C co-infectione

   

0.58

  

1.00

 Chronic infection

16 (6)

31 (21)

1 (11)

 

18 (16)

1 (17)

 

 Exposure and clearance

51 (18)

10 (7)

1 (11)

 

5 (4)

0 (0)

 

 No exposure or infection

189 (68)

99 (66)

6 (67)

 

79 (71)

5 (83)

 
  1. aIn our health system, subjects self-identify as male or female. This information is recorded in the electronic health record
  2. bTime Period 1: 154 had a CD4 cell count measured, Time Period 2: 113 had a CD4 cell count measured
  3. cTime Period 1: 154 had a HIV Viral Load measured, Time Period 2: 113 had a HIV Viral Load measured
  4. dTime Period 1: 146 had HBV serologies measured, Time Period 2: 108 had HBV serologies measured
  5. eTime Period 1: 148 had HCV serologies measured, Time Period 2: 108 had HCV serologies measured
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AIDS Research and Therapy

ISSN: 1742-6405

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