Table 4 Univariate and multivariate analyses of intervention vs. comparison group
Covariate of interest | Univariate | Multivariate | ||
|---|---|---|---|---|
Effect estimate | p value | Effect estimate | p value1 | |
CD4 count (cells/mm3) | ||||
Intervention vs. comparison CD4 change over time | 24.6 (−37.02, 86.23) | 0.4337 | 26.9 (−36.31, 90.19) | 0.4036 |
Intervention | 2.9 (1.19, 4.64) | 0.0009 | 2.7 (0.96, 4.45) | 0.0024 |
Comparison group | 2.8 (0.84, 4.75) | 0.0051 | 2.8 (0.87, 4.79) | 0.047 |
Age | −0.58 (−1.72, 0.56) | 0.3196 | ||
Gender | 40.56 (12.41, 68.72) | 0.0048 | ||
Weight (kg) | ||||
Intervention vs. comparison Weight change over time | 0.9 (−6.97, 8.71) | 0.8270 | −2.64 (−9.91, 4.620) | 0.4757 |
Intervention | 0.14 (−0.073, 0.35) | 0.2000 | 0.27 (0.09, 0.44) | 0.0025 |
Comparison group | 0.15 (−0.03, 0.31) | 0.0968 | 0.14 (−0.34, 0.31) | 0.1234 |
Age | 0.08 (−0.01, 0.17) | 0.0681 | ||
Gender | −0.79 (−3.04, 1.46) | 0.4892 | ||
Hemoglobin (HGB) (in g/dl) | ||||
Intervention vs. comparison HGB change over time | 0.12 (−1.60, 2.05) | 0.8109 | 0.23 (−1.61, 2.06) | 0.7268 |
Intervention | 0.03 (−0.02, 0.09) | 0.2726 | 0.031 (−0.02, 0.09) | 0.0429 |
Comparison group | 0.02 (−0.01, 0.05) | 0.1154 | 0.020 (−0.01, 0.05) | 0.0437 |
Age (in years) | 0.01 (−0.01, 0.03) | 0.2026 | ||
Gender | −0.61 (−1.05, −0.18) | 0.006 | ||
Lost to follow-up | ||||
Intervention vs. comparison | 0.62 (0.51, 0.76) | <0.0001 | 0.64 (0.52, 0.78) | <0.001 |
LTFU change over time | ||||
Intervention | 0.92 (0.91, 0.93) | <0.0001 | 1.01 (1.01, 1.03) | 0.0033 |
Comparison group | 0.93 (0.51, 0.76) | <0.0001 | 0.92 (0.92, 0.93) | <0.001 |
Age | 0.99 (1.00, 1.001) | 0.1737 | ||
Gender | 0.95 (0.89, 1.02) | 0.3169 | ||