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Table 2 Binary and multiple logistic regression model showing determinants of non-adherence to antiretroviral therapy, among adults on ART Aksum town, northern Ethiopia 2015

From: Determinants to antiretroviral treatment non-adherence among adult HIV/AIDS patients in northern Ethiopia

Explanatory variables

Adherence status to ART

COR (95% CI)

AOR (95% CI)

Non-adherent number (%)

Adherent number (%)

Sex

 Male

69 (50.4)

170 (62)

1

1

 Female

68 (49.6)

104 (38)

1.6 (1.1–2.4)

1.4 (0.8–2.4)

Age

 18–29

23 (16.8)

54 (19.7)

1

1

 30–39

60 (43.8)

127 (46.4)

1.1 (0.6–2.0)

1.1 (0.5–2.4)

 40–49

35 (25.5)

74 (27)

1.1 (0.6–2.1)

0.7 (0.3–1.7)

 ≥50

19 (13.9)

19 (6.9)

2.3 (1.1–5.2)

1.7 (0.6–5.0)

Residence

 Urban

114 (83.2)

253 (92.3)

1

1

 Rural

23 (16.8)

21 (76.7)

2.4 (1.3–4.6)

1.4 (0.5–4.0

Occupation

 No occupation

21 (15.3)

42 (15.3)

1

1

 Employed

25 (18.3)

52 (19)

0.9 (0.5–2)

1.4 (0.5–4.2)

 Business

40 (29.2)

96 (35)

0.8 (0.4–1.6)

1.8 (0.7–4.0)

 Farmer

14 (10.2)

10 (3.7)

2.8 (1.1–7.4)

2.3 (0.5–10.3)

 Daily laborer

37 (27)

74 (27)

1 (0.5–1.9)

1.9 (0.8–4.7)

Duration on ART (months)

 6–12

7 (5.1)

38 (13.9)

1

1

 13–24

14 (10.2)

38 (13.9)

2.0 (0.7–5.5)

2 (0.5–8.8)

 ≥25

116 (84.7)

198 (72.2)

3.2 (1.4 7.4)

7 (2.2,22.6)**

ART adverse effect

 Yes

26 (19)

3 (1.1)

21.2 (6.3–71.3)

6.9 (1.4,32.9)**

 No

111 (81)

271 (98.9)

1

1

Substance use

 Yes

21 (15.3)

5 (1.8)

9.7 (3.6–26.5)

5.3 (1.4–20.0)*

 No

116 (84.7)

269 (98.2)

1

1

Live with

 Alone

33 (24.1)

83 (30.3)

1

1

 Parents

18 (13.1)

21 (7.7)

2.2 (1.02–4.6)

3.4 (1.2–10.3)*

 Family

86 (62.8)

170 (62)

1.3 (0.8–2.1)

1.5 (0.8–2.8)

Depression status

 Depressed

41 (29.9)

19 (6.9)

5.7 (3.2–10.4)

3.3 (1.4–7.5)*

 Not depressed

96 (70.1)

255 (93.1)

1

1

CD4 cell count (cells/mm3)

 <350

58 (42.3)

45 (16.4)

3.7 (2.4–6.0)

3.2 (1.8–5.8)*

 ≥350

79 (57.7)

229 (83.6)

1

1

Dietary diversity

 Low

57 (41.6)

43 (15.7)

3.8 (2.4–6.1)

2 (1.1–3.7)*

 Medium and above

80 (58.4)

231 (84.3)

1

1

Daily eating pattern

 ≤2 meals

69 (50.4)

103 (37.6)

1.7 (1.1–2.6)

1.01 (0.6–1.8)

 ≥3 meals

68 (49.6)

171 (62.4)

1

1

Opportunistic infection

 Yes

28 (20.4)

5 (1.8)

13.8 (5.2–36.7)

3.6 (1–13.1)

 No

109 (79.6)

269 (98.2)

1

1

Reminder use

 Yes

127 (92.7)

268 (97.8)

0.3 (0.1–0.8)

0.5 (0.–2.0)

 No

10 (7.3)

6 (2.2)

1

1

Stigma

 Yes

17 (12.4)

10 (3.6)

3.7 (1.7–8.4)

2.8 (0.9–8.5)

 No

120 (87.6)

264 (96.4)

1

1

WHO stage

 Stage I

16 (11.7)

68 (24.8)

1

1

 Stage II and above

121 (88.3)

206 (75.2)

2.5 (1.4–4.5)

1.6 (0.8–3.5)

BMI

 Under weight

38 (27.7)

41 (15)

1

1

 Normal

97 (70.8)

224 (81.7)

0.5 (0.3–0.8)

0.7 (0.3–1.3)

 Over weight

2 (1.5)

9 (3.3)

0.2 (0.1–1.2)

0.4 (0.01–3.0)

Treatment other than ART

 Yes

41 (29.9)

40 (14.6)

2.5 (1.5–4.1)

1.4 (0.7–3.0)

 No

96 (70.1)

234 (85.4)

1

1

  1. * p < 0.05
  2. ** p < 0.001