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Table 2 Drug resistance in ART-Naïve participants and participants experiencing treatment failure according to drug classes

From: HIV-1 drug-resistant mutations and related risk factors among HIV-1-positive individuals experiencing treatment failure in Hebei Province, China

Drug classes

ART-naïve (%)

ART-failure (%)

χ2

p

PIs

3 (2.5)

6 (2.8)

0.000

1.000

NRTIs

2 (1.7)

9 (4.2)

0.816

0.366

NNRTIs

1 (0.8)

23 (10.7)

9.689

0.002

Dual resistance to PIs and NRTIs

0 (0.00)

1 (0.5)

F

1.000

Dual resistance to PIs and NNRTIs

0 (0.00)

6 (2.8)

F

0.093

Dual resistance to NRTIs and NNRTIs

1 (0.8)

63 (29.4)

39.958

<0.001

Multiple resistance to PIs, NRTIs and NNRTIs

0 (0.00)

3 (1.4)

F

0.555

Susceptibility

101 (85.6)

103 (48.1)

45.059

<0.001

  1. PIs protease inhibitors, NRTIs nucleoside reverse transcriptase inhibitors, NNRTIs non-nucleoside reverse transcriptase inhibitors, the mutation classes were exclusive of each other in the study population, F Fisher’s exact test