Table 3 Random-effect linear regression analysis of trend of CD4+ count (slope, cells/mm3/6 month) at JUSH, September 2012 to July 2014
Variable | Unadjusted | Adjusted | ||
|---|---|---|---|---|
B [95% CI] | P value | B [95% CI] | P value | |
Sex | ||||
Male | 0 | 0 | ||
Female | 52.373 [21.22, 84.24] | 0.001 | 33.86 [33.11, 43.24] | 0.013 |
Age | ||||
<25 | 0 | 0 | ||
25–45 | −53.15 [−90.03, −16.27] | 0.005 | −27.32 [−59.3, 4.66] | 0.094 |
>45 | −120.87 [−191.24, −50.49] | 0.001 | −66.19 [−126.68, −5.70] | 0.032 |
BMI | ||||
<18.5 | −48.08 [−80.42, −15.74] | 0.004 | −32.77 [−60.16, −4.27] | 0.011 |
≥18.5 | 0 | 0 | ||
Educ. level | ||||
Illiterate | −0.5 [−42.86, 41.86] | 0.982 | ||
Primary | 14.42 [−19.59, 48.44] | 0.406 | ||
Post-primary | 0 | |||
Residence | ||||
Urban | 0 | |||
Rural | −12.35 [−47.18, 22.54] | 0.488 | ||
Occupation | ||||
Employed | 0 | 0.936 | 0 | 0.796 |
Unemployed | −1.40 [−32.23, 32.44] | 0.015 | 3.96 [−26.04, 33.95] | 0.293 |
House wife | 51.50 [10.2, 92.80] | 21.35 [−18.42, 61.12] | ||
Marital status | ||||
Single | 30.25 [−11.18, 71.68] | 0.152 | 40.45 [0.52, 80.37] | 0.069 |
Married | 0 | 0.525 | 0 | |
Divorced | 13.06 [−27.17, 53.29] | 0.513 | 6.42 [−32.27, 45.11] | 0.745 |
Widowed | −19.89 [−79.56, 39.77] | −2.33 [−55.27, 50.6] | 0.931 | |
Religion | ||||
Orthodox | 0 | 0 | ||
Muslim | 22.91 [−12.00, 57.83] | 0.198 | 20.83 [−8.86, 50.53] | 0.166 |
Other | 0.21 [−40.70, 41.13] | 0.992 | −12.09 [−46.89, 22.71] | 0.496 |
Alcohol | ||||
Yes | −26.1 [−62.15, 9.94] | 0.156 | 8.48 [−22.88, 39.83] | 0.596 |
No | 0 | 0 | ||
ART regimen | ||||
TDF | 11.58 [−18.98, 42.15] | 0.458 | 34.08 [7.80, 60.35] | 0.027 |
AZT | 0 | 0 | ||
Baseline CD4+ count | 0.97 [0.80, 1.15] | 0.000 | 0.879 [0.70, 1.06] | 0.000 |
WHO stage | ||||
I | 0 | |||
II | −16.76 [−57.59, 24.06] | 0.421 | ||
III | −23.17 [−64.32, 17.97] | 0.270 | ||
IV | −29.27 [−86.35, 27.81] | 0.315 | ||
TB (treatment) | ||||
No | 0 | 0 | ||
Yes | −48.18 [−85.37, 5.00] | 0.081 | −20.74 [−59.05, 17.57] | 0.289 |
Prophylaxis | ||||
CPT+ INH | 0 | 0 | ||
CPT alone | −29.40 [−65.65, 6.85] | 0.112 | −10.34 [−40.57, 19.88] | 0.502 |
Neither | −40.89 [−97.93, 16.16] | 0.160 | −22.3 [−70.33, 25.73] | 0.363 |