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Table 3 Random-effect linear regression analysis of trend of CD4+ count (slope, cells/mm3/6 month) at JUSH, September 2012 to July 2014

From: Immunological outcomes of Tenofovir versus Zidovudine-based regimens among people living with HIV/AIDS: a two years retrospective cohort study

Variable Unadjusted Adjusted
B [95% CI] P value B [95% CI] P value
Sex
 Male 0   0  
 Female 52.373 [21.22, 84.24] 0.001 33.86 [33.11, 43.24] 0.013
Age
 <25 0   0  
 25–45 −53.15 [−90.03, −16.27] 0.005 −27.32 [−59.3, 4.66] 0.094
 >45 −120.87 [−191.24, −50.49] 0.001 −66.19 [−126.68, −5.70] 0.032
BMI
 <18.5 −48.08 [−80.42, −15.74] 0.004 −32.77 [−60.16, −4.27] 0.011
 ≥18.5 0   0  
Educ. level
 Illiterate −0.5 [−42.86, 41.86] 0.982   
 Primary 14.42 [−19.59, 48.44] 0.406   
 Post-primary 0    
Residence
 Urban 0    
 Rural −12.35 [−47.18, 22.54] 0.488   
Occupation
 Employed 0 0.936 0 0.796
 Unemployed −1.40 [−32.23, 32.44] 0.015 3.96 [−26.04, 33.95] 0.293
 House wife 51.50 [10.2, 92.80]   21.35 [−18.42, 61.12]  
Marital status
 Single 30.25 [−11.18, 71.68] 0.152 40.45 [0.52, 80.37] 0.069
 Married 0 0.525 0  
 Divorced 13.06 [−27.17, 53.29] 0.513 6.42 [−32.27, 45.11] 0.745
 Widowed −19.89 [−79.56, 39.77]   −2.33 [−55.27, 50.6] 0.931
Religion
 Orthodox 0   0  
 Muslim 22.91 [12.00, 57.83] 0.198 20.83 [−8.86, 50.53] 0.166
 Other 0.21 [40.70, 41.13] 0.992 −12.09 [−46.89, 22.71] 0.496
Alcohol
 Yes 26.1 [62.15, 9.94] 0.156 8.48 [−22.88, 39.83] 0.596
 No 0   0  
ART regimen
 TDF 11.58 [−18.98, 42.15] 0.458 34.08 [7.80, 60.35] 0.027
 AZT 0   0
Baseline CD4+ count 0.97 [0.80, 1.15] 0.000 0.879 [0.70, 1.06] 0.000
WHO stage
 I 0    
 II −16.76 [−57.59, 24.06] 0.421   
 III −23.17 [−64.32, 17.97] 0.270   
 IV −29.27 [−86.35, 27.81] 0.315   
TB (treatment)
 No 0   0  
 Yes −48.18 [−85.37, 5.00] 0.081 −20.74 [−59.05, 17.57] 0.289
Prophylaxis
 CPT+ INH 0   0  
 CPT alone −29.40 [−65.65, 6.85] 0.112 −10.34 [−40.57, 19.88] 0.502
 Neither −40.89 [−97.93, 16.16] 0.160 −22.3 [−70.33, 25.73] 0.363