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Table 3 Hazard ratios for pre-ART attrition

From: Trends in clinical characteristics and outcomes of Pre-ART care at a large HIV clinic in Nairobi, Kenya: a retrospective cohort study

Unadjusted and adjusted hazard ratios for pre-ART attrition

Enrolment characteristic

Unadjusted

Adjusted

HR (95% CI)

p value

HR (95% CI)

p value

Gender

Female

Ref

Ref

Ref

Ref

Male

1.71 (1.47–1.99)

0.0001

1.98 (1.69–2.33)

0.0001

Age

15–19

1.75 (0.98–3.13)

0.0596

1.39 (0.76–2.54)

0.2833

20–24

2.55 (1.99–3.28)

0.0001

1.80 (1.37–2.37)

0.0001

25–34

1.25 (1.05–1.50)

0.0133

1.22 (1.01–1.47)

0.0364

35–44

Ref 

Ref

Ref 

Ref

45–54

0.78 (0.59–1.02)

0.0683

0.77 (0.59–1.02)

0.0680

≥55

0.58 (0.34–0.98)

0.0416

0.68 (0.40–1.16)

0.1526

Marital status

Single

1.81 (1.53–2.14)

0.0001

1.55 (1.29–1.86)

0.0001

Married

Ref

Ref

Ref

Ref

Divorced

1.13 (0.82–1.55)

0.4533

1.41 (1.02–1.95)

0.0370

Widowed

0.72 (0.52–1.00)

0.0511

1.02 (0.73–1.44)

0.8907

Not documented

1.68 (1.20–2.36)

0.0024

1.53 (1.08–2.17)

0.0164

Residency

Rural

Ref

Ref

Ref

Ref

Urban

1.80 (1.39–2.32)

0.0001

1.83 (1.40–2.38)

0.0001

Not documented

2.18 (1.55–3.07)

0.0001

0.97 (0.68–1.39)

0.8573

Care entry point

VCT

Ref

Ref

Ref

Ref

PMTCT

0.47 (0.36–0.61)

0.0001

0.54 (0.41–0.71)

0.0001

TB clinic

0.48 (0.34–0.67)

0.0001

0.55 (0.39–0.78)

0.0007

In patient

0.82 (0.60–1.11)

0.2018

1.02 (0.74–1.40)

0.9082

Other facility

0.82 (0.45–1.50)

0.526

1.00 (0.54–1.85)

0.9937

Other sourcea

1.32 (1.02–1.69)

0.0334

0.99 (0.76–1.28)

0.9177

Not documented

1.43 (1.16–1.76)

0.0008

1.52 (1.21–1.90)

0.0003

HIV diagnosis to care entry

12 months or less

Ref

Ref

Ref

Ref

More than 12 months

1.18 (0.86–1.62)

0.3123

1.32 (0.96–1.83)

0.0916

Not documented

1.92 (1.64–2.24)

0.0001

1.03 (0.86–1.24)

0.7452

Clinical stage

WHO stage 1&2

Ref

Ref

Ref

Ref

WHO stage 3&4

0.76 (0.62–0.94)

0.0119

0.83 (0.66–1.05)

0.1222

Not documented

14.5 (12.1–17.5)

0.0001

10.5 (8.03–13.6)

0.0001

CD4 count

0–100

1.30 (0.81–2.10)

0.2802

1.633 (1.003–2.658)

0.0486

101–200

1.22 (0.73–2.04)

0.442

1.42 (0.85–2.37)

0.1856

201–250

0.69 (0.32–1.51)

0.3579

0.73 (0.34–1.60)

0.4358

251–350

Ref

Ref

Ref

Ref

351–500

1.45 (0.96–2.18)

0.0796

1.51 (1.00–2.29)

0.0506

>500

2.09 (1.43–3.05)

0.0001

2.14 (1.46–3.14)

0.0001

Not documented

5.86 (4.03–8.52)

0.0001

2.98 (2.00–4.44)

0.0001

Opportunistic infections (OI)

  

Any OI

0.49 (0.41–0.57)

0.0001

0.91 (0.76–1.10)

0.3419

  1. Italic values indicate statistically significant (p < 0.05) adjusted Hazard Ratios with corresponding 95% Confidence Intervals
  2. aOther patient source includes out-patient, KNH CCC and others. PMTCT prevention of mother to child transmission
  3. VCT voluntary counselling and testing; TB tuberculosis
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AIDS Research and Therapy

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