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Table 3 Hazard ratios for pre-ART attrition

From: Trends in clinical characteristics and outcomes of Pre-ART care at a large HIV clinic in Nairobi, Kenya: a retrospective cohort study

Unadjusted and adjusted hazard ratios for pre-ART attrition
Enrolment characteristic Unadjusted Adjusted
HR (95% CI) p value HR (95% CI) p value
Gender
Female Ref Ref Ref Ref
Male 1.71 (1.47–1.99) 0.0001 1.98 (1.69–2.33) 0.0001
Age
15–19 1.75 (0.98–3.13) 0.0596 1.39 (0.76–2.54) 0.2833
20–24 2.55 (1.99–3.28) 0.0001 1.80 (1.37–2.37) 0.0001
25–34 1.25 (1.05–1.50) 0.0133 1.22 (1.01–1.47) 0.0364
35–44 Ref  Ref Ref  Ref
45–54 0.78 (0.59–1.02) 0.0683 0.77 (0.59–1.02) 0.0680
≥55 0.58 (0.34–0.98) 0.0416 0.68 (0.40–1.16) 0.1526
Marital status
Single 1.81 (1.53–2.14) 0.0001 1.55 (1.29–1.86) 0.0001
Married Ref Ref Ref Ref
Divorced 1.13 (0.82–1.55) 0.4533 1.41 (1.02–1.95) 0.0370
Widowed 0.72 (0.52–1.00) 0.0511 1.02 (0.73–1.44) 0.8907
Not documented 1.68 (1.20–2.36) 0.0024 1.53 (1.08–2.17) 0.0164
Residency
Rural Ref Ref Ref Ref
Urban 1.80 (1.39–2.32) 0.0001 1.83 (1.40–2.38) 0.0001
Not documented 2.18 (1.55–3.07) 0.0001 0.97 (0.68–1.39) 0.8573
Care entry point
VCT Ref Ref Ref Ref
PMTCT 0.47 (0.36–0.61) 0.0001 0.54 (0.41–0.71) 0.0001
TB clinic 0.48 (0.34–0.67) 0.0001 0.55 (0.39–0.78) 0.0007
In patient 0.82 (0.60–1.11) 0.2018 1.02 (0.74–1.40) 0.9082
Other facility 0.82 (0.45–1.50) 0.526 1.00 (0.54–1.85) 0.9937
Other sourcea 1.32 (1.02–1.69) 0.0334 0.99 (0.76–1.28) 0.9177
Not documented 1.43 (1.16–1.76) 0.0008 1.52 (1.21–1.90) 0.0003
HIV diagnosis to care entry
12 months or less Ref Ref Ref Ref
More than 12 months 1.18 (0.86–1.62) 0.3123 1.32 (0.96–1.83) 0.0916
Not documented 1.92 (1.64–2.24) 0.0001 1.03 (0.86–1.24) 0.7452
Clinical stage
WHO stage 1&2 Ref Ref Ref Ref
WHO stage 3&4 0.76 (0.62–0.94) 0.0119 0.83 (0.66–1.05) 0.1222
Not documented 14.5 (12.1–17.5) 0.0001 10.5 (8.03–13.6) 0.0001
CD4 count
0–100 1.30 (0.81–2.10) 0.2802 1.633 (1.003–2.658) 0.0486
101–200 1.22 (0.73–2.04) 0.442 1.42 (0.85–2.37) 0.1856
201–250 0.69 (0.32–1.51) 0.3579 0.73 (0.34–1.60) 0.4358
251–350 Ref Ref Ref Ref
351–500 1.45 (0.96–2.18) 0.0796 1.51 (1.00–2.29) 0.0506
>500 2.09 (1.43–3.05) 0.0001 2.14 (1.46–3.14) 0.0001
Not documented 5.86 (4.03–8.52) 0.0001 2.98 (2.00–4.44) 0.0001
Opportunistic infections (OI)   
Any OI 0.49 (0.41–0.57) 0.0001 0.91 (0.76–1.10) 0.3419
  1. Italic values indicate statistically significant (p < 0.05) adjusted Hazard Ratios with corresponding 95% Confidence Intervals
  2. aOther patient source includes out-patient, KNH CCC and others. PMTCT prevention of mother to child transmission
  3. VCT voluntary counselling and testing; TB tuberculosis