From: Stem cell transplantation in strategies for curing HIV/AIDS
Year | Improvement | Ref |
---|---|---|
1981 | Cell transfer without conditioning | [44] |
1984 | Syngeneic SCT | [45] |
1988 | SCT together with anti HIV medication (Suramin) | [46] |
1989 | Allogeneic SCT | [47] |
1990 | Use of anti-retrovirals during SCT | [48] |
2001 | Allogeneic SCT combined with gene therapy | [49] |
2005 | Cord blood for SCT | [50] |
2007 | SCT with a CCR5-d32 homozygous graft | [10] |
2010 | In vivo (animal) modification of hematopoietic stem cells using zing fingers | [51] |
2013 | Combined CCR5-d32 cord blood with haplo bride | [52] |
2016 | Generating multi-HIV-antigen specific T-cells | [24] |