Skip to main content

Table 1 Major development steps of the cell or stem cell based HIV therapy during the last decades

From: Stem cell transplantation in strategies for curing HIV/AIDS

Year

Improvement

Ref

1981

Cell transfer without conditioning

[44]

1984

Syngeneic SCT

[45]

1988

SCT together with anti HIV medication (Suramin)

[46]

1989

Allogeneic SCT

[47]

1990

Use of anti-retrovirals during SCT

[48]

2001

Allogeneic SCT combined with gene therapy

[49]

2005

Cord blood for SCT

[50]

2007

SCT with a CCR5-d32 homozygous graft

[10]

2010

In vivo (animal) modification of hematopoietic stem cells using zing fingers

[51]

2013

Combined CCR5-d32 cord blood with haplo bride

[52]

2016

Generating multi-HIV-antigen specific T-cells

[24]