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Table 3 Associated factors with DNA PCR positivity at 6–8 weeks of age

From: Early infant diagnosis of HIV infection using DNA-PCR at a referral center: an 8 years retrospective analysis

Variable

DNA-PCR result

p value

Crude OR (95 % CI)

Adjusted OR (95 % CI)

Positive (%)

Negative (%)

Sex

  

0.992

  

Male

14 (4.3)

309 (95.7)

0.992

1.00 (0.46–2.17)

 

Female

13 (4.3)

288 (95.7)

 

Ref

 

Place of birth

  

0.016

  

Health facility

19 (3.6)

506 (96.4)

 

Ref

Ref

Home

6 (10.9)

49 (89.1)

 

3.26 (1.24–8.53)

3.10 (0.53–18.24)

Type of feeding

  

0.104

  

Exclusive BF

16 (3.2)

478 (96.8)

 

Ref

 

Exclusive RF

6 (6.5)

85 (93.5)

 

2.11 (0.80–5.54)

 

Mixed feeding

3 (6.9)

28 (93.1)

 

0.66 (0.16–2.81)

 

Infant PMTCT

  

0.000a

 

Sdb NVP or none

13 (11.2)

103 (88.8)

   

Sd NVP + AZT

11 (3.9)

268 (96.1)

   

Sd NVP ≥6 weeks

0 (0)

191 (100)

   

Mother CD4 during pregnancy

  

0.033

  

<100/mm3

3 (17.6)

14 (82.4)

 

5.68 (1.15–28.05)

4.50 (0.71–28.56)

100–500/mm3

3 (1.3)

236 (98.7)

 

0.34 (0.08–1.53)

0.26 (0.05–1.33)

>500/mm3

4 (3.6)

106 (96.4)

 

Ref

Ref

Mother WHO stage

  

0.344

  

WHO stage 1

7 (3.3)

204 (96.7)

 

Ref

 

WHO stage 2

2 (2.1)

91 (97.9)

 

0.64 (0.13–3.14)

 

WHO stage 3/4

6 (6)

93 (94)

 

1.88 (0.62–5.75)

 

Mother any PMTCT

  

0.000

  

No

13 (12.7)

89 (87.3)

 

6.10 (2.45–15.17)

3.80 (0.68–21.09)

Yes

8 (2.3)

334 (97.7)

 

Ref

Ref

Type of PMTCT (mother)

  

0.402

  

AZT only

2 (4)

48 (96)

 

2.01 (0.39–10.24)

 

HAART

6 (2)

289 (98)

 

Ref

 

Antenatal care follow up

  

0.000

  

No

11 (12.8)

75 (87.2)

 

5.54 (2.27–13.52)

4.05 (0.25–65.75)

Yes

10 (2.6)

378 (97.4)

 

Ref

Ref

Mother care and treatment

  

0.003

  

Enrolled in care and Rxc

14 (3.3)

406 (96.7)

 

Ref

Not enrolled

7 (13)

47 (87)

 

4.32 (1.66–11.24)

 
  1. a X 2 test was used
  2. bSingle dose
  3. cTreatment