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Table 3 Associated factors with DNA PCR positivity at 6–8 weeks of age

From: Early infant diagnosis of HIV infection using DNA-PCR at a referral center: an 8 years retrospective analysis

Variable DNA-PCR result p value Crude OR (95 % CI) Adjusted OR (95 % CI)
Positive (%) Negative (%)
Sex    0.992   
Male 14 (4.3) 309 (95.7) 0.992 1.00 (0.46–2.17)  
Female 13 (4.3) 288 (95.7)   Ref  
Place of birth    0.016   
Health facility 19 (3.6) 506 (96.4)   Ref Ref
Home 6 (10.9) 49 (89.1)   3.26 (1.24–8.53) 3.10 (0.53–18.24)
Type of feeding    0.104   
Exclusive BF 16 (3.2) 478 (96.8)   Ref  
Exclusive RF 6 (6.5) 85 (93.5)   2.11 (0.80–5.54)  
Mixed feeding 3 (6.9) 28 (93.1)   0.66 (0.16–2.81)  
Infant PMTCT    0.000a  
Sdb NVP or none 13 (11.2) 103 (88.8)    
Sd NVP + AZT 11 (3.9) 268 (96.1)    
Sd NVP ≥6 weeks 0 (0) 191 (100)    
Mother CD4 during pregnancy    0.033   
<100/mm3 3 (17.6) 14 (82.4)   5.68 (1.15–28.05) 4.50 (0.71–28.56)
100–500/mm3 3 (1.3) 236 (98.7)   0.34 (0.08–1.53) 0.26 (0.05–1.33)
>500/mm3 4 (3.6) 106 (96.4)   Ref Ref
Mother WHO stage    0.344   
WHO stage 1 7 (3.3) 204 (96.7)   Ref  
WHO stage 2 2 (2.1) 91 (97.9)   0.64 (0.13–3.14)  
WHO stage 3/4 6 (6) 93 (94)   1.88 (0.62–5.75)  
Mother any PMTCT    0.000   
No 13 (12.7) 89 (87.3)   6.10 (2.45–15.17) 3.80 (0.68–21.09)
Yes 8 (2.3) 334 (97.7)   Ref Ref
Type of PMTCT (mother)    0.402   
AZT only 2 (4) 48 (96)   2.01 (0.39–10.24)  
HAART 6 (2) 289 (98)   Ref  
Antenatal care follow up    0.000   
No 11 (12.8) 75 (87.2)   5.54 (2.27–13.52) 4.05 (0.25–65.75)
Yes 10 (2.6) 378 (97.4)   Ref Ref
Mother care and treatment    0.003   
Enrolled in care and Rxc 14 (3.3) 406 (96.7)   Ref
Not enrolled 7 (13) 47 (87)   4.32 (1.66–11.24)  
  1. a X 2 test was used
  2. bSingle dose
  3. cTreatment